Mike and KITT hunt for a pilfered serum that can transform its user into a physically powerful being. Elsewhere, Sarah is overwhelmed by the all-consuming work of her new post.

During his "decompression" time, Mike visits an old hangout---Sonny's Bar---and helps the new proprietress restore the joint to its original glory. But Mike must square off against a mysterious someone who wants the bar sold, and that person may resort to arson to fulfill that desire.

When a plane transporting a 10-year-old federal witness crashes, Mike determines that the accident was faked and that the boy was kidnapped. He clashes with the investigating DEA Agent, who promptly arrests him for interfering with the case. Meanwhile, Sarah fights for more authority over the SSC's future endeavors.

Mike infiltrates an underground fight club to investigate the mysterious death of a hard-nosed drill sergeant.

Mike gets entangled in a bank robbery and becomes one of the robbers' hostages. His effort to stop the thieves gets hampered by twists, turns and uncertainty about the criminals' true motives.

A downcast Sarah skips town in the wake of a tragic family event, and Mike's subsequent search for her yields intriguing answers about his nebulous past. Meanwhile, the NSA gets a green light to activate KITT's evil nemesis, KARR, prompting outrage in Mike and the gang.

Mike and KITT continue their high-octane mission to foil a terrorist and rescue an ambassador. But the quest turns even more perilous when a bomb is placed inside KITT---and it will explode if the car is driven below a certain speed. Meanwhile, Sarah receives shocking information about her father.

Mike and KITT rev up to rescue a snatched foreign ambassador from the clutches of a deranged terrorist. Elsewhere, Sarah and Dr. Graiman team up to repair a damaged robot.

The spread of a devastating computer virus jeopardizes the entire world. It could also mean the ultimate stall out for KITT, who becomes infected by the big bug. Elsewhere, Mike's jealousy grows when Sarah reconnects with her ex-beau.

Mike, Billy and KITT go full throttle to bust a money-laundering ring---with Billy finding a bit of romance in the process. Elsewhere, Dr. Graiman tangles with a foe (and flame) from his past.

Mike and KITT rev up to take down a politically connected criminal couple who are out to reveal classified information related to Knight Industries.

There's a big bad trick on Halloween when an intruder kills a tech inside Knight Industry headquarters. Meanwhile, a storm strands Mike and Sarah on a flight as they race against time to save KITT from self-destruction.

Mike poses as a marine to thwart a rogue military officer's explosive scheme to blow up a dam. Helping him in the mission: a beautiful undercover agent. Elsewhere, Billy is tutored in the fine art of combat.

A lethally poisoned Mike must fake the assassination of a tech bigwig in order to obtain the antidote. Meanwhile, hallucinations and the reemergence of an enigmatic woman shine light on Mike's hazy past.

Mike and Zoe arrive in Mexico, masquerading as surfing honeymooners in an undercover mission to thwart a plot to smuggle terrorist weapons into the U.S. Sarah and Billy are also on the case---but surprising developments jeopardize the assignment.

Mike reunites with a former Army buddy to bring down a drag racing gang that is smuggling weapons overseas. Sarah joins Mike and KITT on this dangerous undercover mission, much to her father's dismay.

Mike goes after a woman from his past who abducts a man whose DNA contains a key to an unbreakable code.

The new KITT (Knight Industries Three Thousand) is the coolest car ever created and someone is willing to do anything to obtain it. Sarah Graiman is a 24-year old PhD candidate at Stanford, following in her genius father Charles' footsteps. When she receives word from KITT that her father is missing, they set out to find and recruit childhood pal and former boyfriend Mike Traceur to help uncover who is behind the attempt to procure KITT and locate Charles.