Morris faces a complicated case involving a young girl hit while riding her bicycle. Gates finds it very difficult to let go of his feelings for Sam. Neela becomes quite flustered when Brenner returns from Australia. Dr. Banfield and her husband are at the fertilization clinic hoping for their one in a million chance. And an older woman is brought in assisted by her on-again, off-again husband.

A car accident in the ambulance bay injures a woman with a young child and leaves the mother in need of surgery with a significant recovery time. Brenner has difficulty finding a family member to care for the daughter. Gates treats an elderly patient who refuses treatment because he's afraid his condition will prolong an inevitable death. Morris impresses Claudia and her family. Neela tells Brenner about her job offer from North Carolina.