ER ends its 15 year run with a two hour episode. Gates works on a young teen suffering from alcohol poisoning after playing a drinking game. Old friends come show their support when a new medical facility for the underprivileged is opened. Sam receives a special gift for her birthday. Carter and a new intern try to save a mother in labor with twins.

The cast and crew reflect on 15 years in the ER. From the pilot to the finale the stories from Country General have impacted audiences all around the world. Now, the most recognized drama bids farewell.

The ER doctors and nurses help out at Camp Del Corazon, a camp for kids who have had open-heart surgery, working alongside the camp counselor (guest star TOM ARNOLD).

Neela proves her worth as attending material when she clashes with Dubenko on how to proceed with two different surgical cases. Brenner gains a deep insight into his painful childhood.

A girl drops off a sick baby at the ER and then leaves; Carter may get a kidney transplant; Gates and Daria care for an elderly woman with multiple sclerosis; Neela and Sam are in Seattle to transport a heart for Joanie Moore, while Doug and Carol are concerned that the donor's grandmother might not consent.

A camera crew shooting footage for a documentary interviews members of the ER staff. Detective Claudia Diaz is brought in, critically injured with gunshot wounds. Neela laments the lack of communication between her and Brenner. Sam struggles to reconcile with her mother. Carter's condition worsens quite suddenly.

BThe Banfields explore their options with an adoption agency. Carter holds his own in spite of the procedural and technological advances made to emergency medicine since he's been gone. Brenner has concerns about Lucy's foster family. Morris treats a couple who takes his advice a little too far. Sam gets quite the shock when her mother comes into the ER. Neela makes a decision about her future. Banfield discovers Carter's secret.

Valentine's Day in the ER finds Neela spellbound by Brenner. Determined to have a baby, Banfield comes up with a plan but has difficulty getting her husband on board. Neela performs surgery on a young girl's mother. Dr. Carter surprises the staff with a visit to the ER. Gates treats a strange patient who may have ingested a toxin while hunting for mushrooms.

A car accident in the ambulance bay injures a woman with a young child and leaves the mother in need of surgery with a significant recovery time. Brenner has difficulty finding a family member to care for the daughter. Gates treats an elderly patient who refuses treatment because he's afraid his condition will prolong an inevitable death. Morris impresses Claudia and her family. Neela tells Brenner about her job offer from North Carolina.

Gates and Morris tend to an elderly man who was assaulted on the street. Sam's sister shows up unexpectedly. Brenner and Dubenko clash while treating a mother thought to have late stage cancer. Dr. Morgenstern returns to the ER to assist a former mentor who is seriously ill.

A girl who was hit by a car while driving a bicycle is treated in the ER. When her boyfriend turns up it turns out it may not have been an accident. While a lottery has made millionaires of several nearby convenience store workers, Dr. Banfield and her husband are at the fertilization clinic hoping for their one in a million chance. And as an older woman is brought in assisted by her on-and-off husband, three love stories continue in the ER: Dr. Morris meets policewoman Diaz again, Sam discovers that Tony has been seeing Daria, and Neela plays it cool with the ...

Neela has recurring dreams about trying to save a girl with sickle cell anemia. In them she also goes to an attending interview and sees an old colleague, has conversations with Ray, welcomes Brenner back from Australia, and assists Gates and Banfield in trying to save a "dream runner" who jumped out of a window during his sleep.

When a drug deal goes bad, two brothers sustain serious injuries and are brought to the ER. Tensions continue between Gates and Sam, coming to a head when Tony is the last to know Alex is about to be released from the hospital. Neela has to tell a young girl with sickle cell anemia that she must have an operation, and the case leads her to consider specializing in pediatric surgery. A feisty patient takes Morris into her confidence. Banfield ponders her choices about expanding her family.

The Last One Before Christmas Break. The one in which Frank and Drs. Sanchez and Wade accidentally get cake with cannabis in it. The one with the Christmas party. Archie's cousin brings Archie's dead father's storage container to the ER bay. An injured pregnant Latino woman is brought in. There is something wrong with her baby. Plus, the Immigration Office wants to deport her. How's it end? It's Christmas - what do you think?

As a snowstorm hits Chicago, Sam's son Alex crashes a car and ends up in critical condition in the ER. Neela gives a deposition in the malpractice suit against her. Dr. Morris and Dr. Banfield are both at a medical conference in Omaha, and when the snow cancels all flights out they share a memorable and surprising evening.

A woman who broke her leg while trying to escape a house fire is brought in with her husband. The husband, Mr. Lotery did not let the paramedics to check him over. Then his brother-in-law arrives, saying that he predicted that something like the house fire would happen - it was actually an arson. Mr. Lotery's brother-in-law becomes aggressive and accuses him of being a pervert, specifically a pedophile. Mr. Lotery denies the accusations. He was sued but found not guilty. When Mr. Lotery is waiting for his wife who's in line for X-ray, he has the chance to calm down a ...

Trying to rescue a three-year-old girl from drowning in a nearby lake, Banfield is reminded of her own experience at County with Dr. Greene (ANTHONY EDWARDS) caring for her son.

COURTNEY B. VANCE guest stars in an episode when everybody seems to know best. Both Morris and Neela have authority issues with Dr. Banfield and Gates upsets Sam.

Patients include an 18-year-old who was stabbed with a fork at his school, and a man shot by a cop at a Halloween party. Meanwhile Sam is annoyed by Gates and Daria.

When a thirteen-year-old gymnast is brought into the hospital after having supposedly fallen off a wall, Dr. Banfield and Dr. Gates must sort out whether abuse is involved.

When a gunshot wound victim arrives, the new chief and Abby butt heads on how to treat the patient. Abby comes to Sam's defense when she goes before a nurses disciplinary board.

Everyone in the ER is trying to cope with the loss of their colleague. The staff feels defensive toward the new Chief and her tough disposition. Gates and the new interns treat a bio terrorist, who has a lethal secret that endangers them all. Neela makes a great effort to get Dubenko back on the surgery staff, and gets help from an unexpected souce.

The 15th and final season of ER begins with the devastating repercussions of the ambulance explosion. As Morris and Neela do everything they can to save a wounded colleague, Abby treats a young girl injured during the blast.