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Don and his team must stop a suspected serial killer who drugs and kills young women.
Don enlists Charlie's help when the bodies of five young Asian girls found washed up are suspected of being infected with the Avian influenza virus.
Don and his family are in danger when they become the targets of the suspects Don and the team are investigating.
When an assailant storms the FBI office with a gun, Charlie gets caught in the crossfire between the suspect and the FBI agents.
Don takes a deeper look at his life after he investigates the circumstances surrounding an ex-girlfriend's death.
Don and his team investigate a school shooting only to be surprised with one of the suspects.
The FBI investigates the murder of a female Iraqi activist which happened on U.S. soil.
When a psychic leads authorities to a deadly crime scene, Charlie sets out to prove it is just a fluke.
An anti-war bombing which kills an innocent man becomes personal when the investigation reveals surprising information about Don and Charlie's father's past.
Cal Sci science student becomes the suspect when an expensive piece of equipment is stolen from the school's DNA lab.
The agents must stop an organ trafficking ring when they discover a young immigrant girl died while selling one of her kidneys.
Murder of a young student at a card club leads the FBI to uncover a deadly card counting scheme.
When a fellow FBI agent working undercover is killed in a gang retaliation, Don and his team must investigate.
Don and his team must find the serial arsonist responsible for an innocent man's death.
The murder of a young museum researcher/archaeologist sends the team on a search for her killer and the missing American Indian skull that she was studying.
Former chemist of a large pharmaceutical company is discovered to be tampering with medication and Don and Megan must track him down.
Routine drug bust unveils a sensitive issue which Charlie takes to heart.
When a father is killed in a home robbery, Don and his team investigate the connection between several recent robberies in the upscale community.
Don and his agents must uncover who interfered with a counter-terrorism exercise before deadly results occur.
Don and his team find a suspicious code during a raid which Charlie determines is part of a secret plan to assassinate a Colombian exile living in Los Angeles.
Don and his team must solve the murder of a CFO of a large energy corporation who is found murdered on her doorstep and her young son is the only witness.
Don and his team search for the stalker of a pop princess which turns into a murder investigation of a paparazzo.
Don and his team must find who is responsible for kidnapping the family of a jewelry store owner before they are killed.
Don uses Charlie and Megan's expertise when the FBI is called to the scene of a federal judge's wife's murder.