The doctors visit their alma mater for a class reunion and become professors for a day; a shih tzu is rushed to the clinic after swallowing a large piece of rawhide, while the owner of a pit bull with a deformed leg must consider drastic surgery.

Dr. Blue flies into action when a rottweiler in labor gets rushed into the hospital with two puppies stuck inside her; the three vets grab the reins and their cowboy hats to ride horseback into town for Houston's biggest rodeo parade.

The doctors all want to be the one who goes to a vet conference in San Diego; Dr. Ross treats a young kinkajou, while Dr. Blue treats a Min Pin's drop-dead breath; Dr. Lavigne suspects a cat has a contagious disease.

Dr. Blue discovers a huge problem for a paralyzed Yorkie; Dr. Ross takes care of a pair of post-scuffle roosters, before joining Dr. Lavigne on a hyena consultation; the Lavigne family hosts a dinner party showcasing Anne's cooking skills.

Dr. Ross and vet tech Kyerra race to save a stray cat horrifically mangled by a car engine; the Rosses move into their new home while Dr. Blue treats a 700-pound arthritic pig; Dr. Lavigne hears a rescue Chihuahua's incredible story.

It's time for Dr. Ross and Tauvia to move out of his momma's house. Dr. Lavigne makes a life or death decision with Diesel, a mastiff who may have a toy lodged in his intestines. Dr. Blue sees a pig with an affection for household furniture.

A health scare ends Dr. Blue's dreams of motorcycle riding with his brother. Dr. Ross treats a sweet bearded dragon who is laying bad eggs, while Dr. Lavigne is challenged with what to do about a large tumor taking over a Boxer's toe.

Dr. Ross treats baby kangaroos and teams up with the owners of a petting zoo to hold an animal awareness event; Dr. Blue removes a mass from a beloved pit-mix; Dr. Lavigne treats a vision- and hearing-impaired Great Dane.