Jools welcomes Florence + The Machine, who recently returned with her fifth album, Dance Fever, her fourth to reach number one. She performs a couple of songs and chats to Jools about the inspirations behind it, including a medieval phenomenon known as choreomania. She also picks and discusses a performance by Nick Cave and the Bad Seeds from the Later... archives.

Three new artists make their TV debut on the show this week. Liverpool breakthrough quartet The Mysterines have already sold out two headline tours and released their debut album Reeling to great acclaim back in March. North west London's teen prodigy and king of bedroom pop Kamal already has the support of Dave. And completing the trio is east London multi-instrumentalist Beyaz, who, as a self-taught musician, has tried his hand at everything from training at a classical conservatoire to drumming in a punk band and producing grime records.

Completing the line-up is indie singer-songwriter Jamie T, who is back with his first new material in six years. He performs his single The Old Style Raiders from upcoming album The Theory of Whatever, which coincides with the 15th anniversary celebrations of his debut offering Panic Prevention, providing an opportunity for him to treat us to a classic from that seminal, platinum-selling record.

And as this week's show falls on the same night Sir Paul McCartney marks his 80th birthday and prepares to headline Glastonbury Festival next week, Jools and the artists celebrate with a group sing-song and a look back in the archives of his performance on the show in 2013.

Returning to the show after an eight-year break, we welcome back Scottish singer-songwriter Paolo Nutini, who performs songs from his upcoming fourth studio album Last Night In The Bittersweet, a record that saw him write over a hundred songs during its making.
 
Making her debut on the show is Bristolian breakthrough artist Katy J Pearson, who is inspired by the likes of Kate Bush and Fleetwood Mac and performs Talk Over Town from her upcoming second LP, which is co-produced by PJ Harvey collaborator Ali Chant and producer of the moment Dan Carey.
 
Jools chats to legendary producer William Orbit about some of the records he has worked on in his career spanning six decades, including albums by Blur, Madonna and U2. He selects a performance from the archive by Amadou & Mariam. William also performs a song with singer-songwriter Polly Scattergood.
 
Returning to the show are twin sisters from Paris, Ibeyi, who have just released their third album Spell 31, which sees them collaborate with Jorja Smith, Pa Salieu and Berwyn. They perform their track Sister 2 Sister, which they say is the first song they've written about their relationship as twins.
 
And also returning are Oxford indie rockers Foals with a couple of tracks from their upcoming new album Life Is Yours, including the single 2am, which was written during lockdown about their longing for nightlife and parties. Frontman Yannis also chats to Jools about the record and his desire to write a traditional Greek music album.

And as part of an evening celebrating Pride month on BBC Two, we delve into the archive to relive the Scissor Sisters debut on the show.

Jools welcomes Londoner Koyej Radical, who after a decade of releasing EPs and projects returns to the show with songs from his debut album Reason to Smile. He also swaps fashion tips with Jools and selects Joy Crookes from the Hootenanny archives.

Leicester's finest, Kasabian, return with a couple of songs from their forthcoming album The Alchemist's Euphoria, co-produced with Fraser T Smith. It's a record that frontman Serge Pizzorno describes as one that 'really holds up in our seven albums - the Magnificent Seven', which is inspired by his recent listening to everything from Kanye to old 70s cuts.

Three artists make their debut this week starting with north west Londoner Knucks, who performs his track Leon the Professional from his debut project Alpha Place, which recently entered the charts at number three. He also joins Kojey on his track Payback, where you can expect some excellent dance moves.

Originally from Virginia and now based between London and NYC is Jazz singer Judi Jackson, who started her career opening for Mavis Staples and working with Grammy-winning outfit Snarky Puppy. She performs her hypnotic torch song River, which she says is about 'the flow of life in music and love'.

And completing the line-up is south London poet, novelist and songwriter Kae Tempest, who will be performing Salt Coast, a track penned as a love letter to the United Kingdom and taken from their fourth solo album The Line is a Curve. Kae chats to Jools and chooses Johnny Cash from the Later... archives.

Jools welcomes a brand new collaboration consisting of Academy Award-nominated actress and singer Jessie Buckley and Brit Award-winning producer and ex-Suede guitarist Bernard Butler, who perform a couple of tracks from their forthcoming album, a collection of 12 mesmerising new songs entitled For All Our Days that Tear the Heart. They chat to Jools about their collaboration and their choices from the Later… archives of performances by Leonard Cohen and Paul Buchanan.

There are three debuts on this week's show, starting with south Londoner Poppy Ajudha, who has collaborated with the likes of Tom Misch and Nubya Garcia and performs her single PLAYGOD from her debut album The Power in Us. The album has been described by critics as a 'genre fluid blend of jazz, R&B, soul, rock and pop' that offers 'powerful therapy in troubled times'. Poppy also performs, with Jools at the piano, a classic song she grew up listening to.

Also making their debut are Brisbane electro-pop quartet Confidence Man, fronted by two powerhouse performers known as Janet Planet and Sugar Bones, who consider the likes of Bono, Noel Gallagher and Elton John amongst their fans. They perform their catchy, infectious tune Holiday, a song that perfectly encapsulates the sound of their latest album Tilt and 'taps into the hedonistic feeling of all the best EDM.'

And completing the line-up are London based rock'n'roll band Warmduscher, who are renowned for their raucous, high-energy performances. Their lineup includes previous members of Fat White Family, and they have just released their fourth LP, At the Hotspot, produced by Hot Chip's Joe Goddard and Al Doyle.

Jools is joined by rock‘n'roll legend Liam Gallagher, who performs a couple of tracks with his band from his forthcoming album C'mon You Know and an exclusive bonus track for BBC iPlayer. Liam also discusses a performance by Jimmy Cliff he has chosen from the Later... archives, as well as revisiting his debut on the show with Oasis from 1994.

Dubliner and debutante Sinead O'Brien shares her spellbinding poetry and songwriting on a performance of her track Holy Country, taken from her forthcoming debut album, which sees the Irish wordsmith experimenting with the form and shape of language.

And we welcome Belgian duo Charlotte Adigéry and Bolis Pupul, who make their debut on the show with their infectious electro-pop sound on a track from their album Topical Dancer, which was produced by fellow Belgians and electro band Soulwax.

And returning to the show is Malian singer Oumou Sangaré, known as the songbird of Wassoulou, to perform a couple of numbers from her thirteenth studio album, Timbuktu. Recorded between the US, Mali and France, it's a fusion of blues, folk, rock and traditional Malian music featuring a Malian lute known as a kamele n'goni.

In a new performance space at the recently restored Alexandra Palace Theatre, Jools is joined by Isle of Wight duo Wet Leg, who rose to prominence last year and recently released their critically acclaimed number one debut record. They are returning to the show after performing their viral hit Chaise Longue last autumn.

Another returnee is US singer and blues guitarist Joe Bonamassa, who is stopping off in north London amidst his UK tour to perform a couple of tracks as well as chatting to Jools and picking a Peter Gabriel track from the Later... archive.

The first of two debuts in this new series comes from Nigerian-born, London-based artist Obongjayar, who has already featured on tracks by the likes of Little Simz and Pa Salieu. He steps into the spotlight to perform a song from his own debut album, Some Nights I Dream Of Doors, after a recent performance at the 6 Music Festival in Cardiff.

And following in the footsteps of past Later... debutantes Adele and Amy Winehouse, BRIT School alumni and south Londoner Cat Burns is also making her debut on the show with her Radio 1 playlisted and top three single Go.