Jessica Alba (The Honest Company); actor Harry Shum Jr.; guest host tWitch.

Allison Janney ("Mom"); Maren Morris (single "Better Than We Found It"); Kalen Allen performs; acrobats perform.

Paula Abdul ("The Masked Dancer").

Samantha Bee ("Full Frontal With Samantha Bee"); chef José Andrés.

Chris Harrison ("The Bachelorette"); Michelle Buteau (book "Survival of the Thickest"); a 6-year-old rapper and his dad perform a holiday song.

James Corden ("The Prom"); Meghan Trainor is interviewed and performs "White Christmas."

Pharrell ("Voices of Fire").

Leslie Odom Jr. is interviewed and performs "Last Christmas."

Chance the Rapper; a dad dances outside a hospital window to cheer his teen son, who is being treated for cancer.

Kate Mara ("A Teacher").

Bryan Cranston ("Your Honor"); Anya Taylor-Joy ("The Queen's Gambit").

Diane Keaton ("Love, Weddings & Other Disasters"); Isla Fisher ("Godmothered").

Aubrey Plaza ("Black Bear"); Lil Nas X (single "Holiday").

Justin Bieber (YouTube's "Justin Bieber: Next Chapter"); Russell Dickerson performs.

Alison Brie ("Happiest Season"); a 5-year-old Dolly Parton fan and her dad perform.

Josh Duhamel ("Buddy Games").

Jake Tapper ("The Lead With Jake Tapper"); a Paralympic downhill skier uses his engineering skills to design adaptive devices for skateboards.

Goldie Hawn and Kurt Russell ("The Christmas Chronicles 2"); Ben Falcone ("Superintelligence").

Guest host Tiffany Haddish.

Melissa McCarthy ("Superintelligence").

Patrick Dempsey ("Devils").

Sarah Paulson and Kiera Allen ("Run").

Matthew McConaughey (book "Greenlights"); Gabby Barrett performs.

Country music icon GARTH BROOKS takes over as guest host! The star is one of the world's best-selling music artists, but today he's turning the tables and interviewing some incredible guests!

Hollywood star VINCE VAUGHN visits Ellen! The actor has been in hit movies like "Swingers," "Anchorman: The Legend of Ron Burgundy," and "Wedding Crashers," and now he's in the new slasher comedy "Freaky"! Vince will chat all about the film and what he's been up to since his last visit!

Get ready to smile from ear to ear, because MARIO LOPEZ is here! The actor and "Access Hollywood" host hit it big over 30 years ago as A.C. Slater in the beloved teen show "Saved by the Bell," and now he's reprising his role in the new reboot on Peacock! He'll chat all about getting back into character and what we can expect in the new series!

Then, boy band WHY DON'T WE will take the stage with their new hit song, "Fallin'"! 

The incredibly talented USHER returns! When he's not in the studio creating megahits, or acting in movies, he's hard at work giving back to the community. Today he'll talk with Ellen about his new non-profit organization, Usher's New Look, which transforms the lives of the under-resourced youth through comprehensive programming, which develops passion-driven, global leaders from middle school through college. Get ready to be "Caught Up" in this show!

Last week, Ellen surprised Shawanda and Jerwayne Terry and their seven kids at their home in Alabama! They talked about adopting five of their children and becoming foster parents in their community. Since they've never taken a vacation, Ellen told them to pack their bags, because they're going on their first trip – to L.A. to see Ellen in person at the show so they can open a huge gift. Now that they're in California, they'll chat with Ellen... and finally get to see what's inside that big present!

Fellow talk show host JIMMY KIMMEL returns to the show! He'll chat about what it was like hosting "Jimmy Kimmel Live!" from home, what it's like being back in the studio, and more! Plus, he'll be joined by a special guest – on-air sidekick Guillermo Rodriguez will team up with Jimmy to play a game of "You Bet Your Wife"! 

Ellen welcomes 6-year-old Sam White and his dad Bobby, who recently went viral with an inspiring video of Sam rapping the #YouCanBeABCs. The song breaks down different professions with every letter of the alphabet, and has been viewed over 15 million times! They'll chat about the song and perform it! 

There's so much more in store, don't miss it!

The always entertaining SARAH SILVERMAN guest hosts the show, and she'll welcome actor ANTHONY ANDERSON! He makes us laugh every week on his hilarious ABC hit show, "Black-ish." He's starred in hit films including "The Departed," "Big Momma's House," and "The Barbershop" franchise. Find out what he's been up to and what we can expect on the new season of "Black-ish"! 

Then, Sarah meets two inspiring frontline workers, Faith Martin and Priscilla Pantoja. Faith is an elementary teacher in Boston who has been going above and beyond for her students, and Priscilla is a nurse who began her career in medicine just as the pandemic started. Sarah and tWitch will play a game with them that ends with a huge prize for each of these incredible people. 

Plus, Sarah has a chat with kids about how they're handling everything going on in 2020! You won't want to miss this!

Lily Tomlin (\"Radium Girls\"); Chelsea Handler plays \"5-Second Rule\"; an 11-year-old magician performs; a man with ALS and his fiancee remain extremely positive.

Magic Johnson discusses his company, EquiTrust, which funds Paycheck Protection Program loans for minority- and women-owned businesses; 24KGoldn performs.

Ellen reminisces about some of her favorite moments on the show throughout the years.

Wanda Sykes; 10-year-old Macey Hensley returns to chat about the importance of voting in the 2020 United States presidential election.

Sacha Baron Cohen (\"Borat Subsequent Moviefilm\" and \"The Trial of the Chicago 7\"); Los Angeles Dodgers pitcher Clayton Kershaw; Sarah Cooper (\"Sarah Cooper: Everything's Fine\").

Howie Mandel; executive producer Andy Lassner attends the Los Angeles Haunted Hayride: Live Drive Up Experience.

Khloé Kardashian ("Keeping Up With the Kardashians," Dose & Co.).

Thomas Middleditch ("B Positive"); Chelsea Handler plays "5 Second Rule."

Justin Hartley ("This Is Us"); mentalist Keith Barry.

Ashley Graham ("Do It for the Graham"); Skai Jackson ("Dancing With the Stars"); SAINt JHN performs; guest host Stephen "tWitch" Boss.

Magic Johnson; mentalist Keith Barry.

Comic Chelsea Handler ("Chelsea Handler: Evolution").

Actress Sarah Hyland ("Lady Parts"); author Chasten Buttigieg ("I Have Something to Tell You").

Ken Jeong ("Over the Moon"); the Boston Celtics' Jaylen Brown; AJR performs.

Marlon Wayans ("On the Rocks"); Ron Finley discusses urban gardening; guest host Tiffany Haddish.

Singer Jason Derulo.

Comic Colin Jost (book "A Very Punchable Face: A Memoir").

Kristen Bell (book "The Tiny Chef"); TV host Steve Spangler.

Ellen's favorite moments so far from Season 18.

Comic Michael Che ("Saturday Night Live"); 9-year-old cellist Cameron Renshaw.

Guest host Tiffany Haddish.

Sarah Silverman ("The Sarah Silverman Podcast"); Jeff Foxworthy cameo; Bon Jovi performs.

Orlando Bloom ("Retaliation"); Gloria Steinem ("The Glorias"); Tig Notaro; a teen who builds and gives away desks to underprivileged children in his community.

Brad Paisley (song "No I in Beer"); Jurnee Smollett ("Lovecraft Country").

Adam Sandler ("Hubie Halloween"); Ellen surprises the Black owner of a women's plus-size thrift store.

Kalen Allen; "World of Dance" winners MDC 3; guest host Stephen "tWitch" Boss.

Chris Rock ("Fargo").

Jason Sudeikis ("Ted Lasso"); a 2-year-old and his grandmother, who are viral video stars.

Amy Schumer; Eric, a 31-year-old firefighter who was diagnosed with ALS just a month after his wedding, and his wife, Amanda.

Blake Shelton (Smithworks Vodka and his hit song "Happy Anywhere," featuring Gwen Stefani); president and co-founder of the Center for Humane Technology Tristan Harris ("The Social Dilemma").

Derek Hough ("Dancing With the Stars"); TikTok star Addison Rae ("Mama Knows Best"); Aloe Blacc performs; guest host Stephen "tWitch" Boss; guest DJ Allison Holker Boss.

Kris Jenner ("Keeping Up With the Kardashians"); a high-school principal who hand-delivered graduation signs to all 220 seniors at their homes, had ceremonies for each of them over the summer, and helps students who don't have WiFi at home.

Alec Baldwin ("Match Game"); SuperM performs.

Actress Kerry Washington talks about her voting initiatives and National Voter Registration Day; W.A.F.F.L.E. Crew dances.

Actress Tiffany Haddish; a first-generation college student gives up his dreams to become the sole caretaker of his six siblings, and now they are in danger of losing their home.

Guest Hosts Jane Fonda and Lily Tomlin

Guest Host Robert Downey Jr.

Dan and Eugene Levy are special guest hosts.