Jennifer Aniston; Billie Eilish; P!nk chats and performs.

Bruno Mars; Ellen surprises The Lucky 13, a group of friends who all met on the show during Season 13 and have stayed in touch throughout the years, been on the show together a handful of times, and continued to give back to the community.

Oprah Winfrey; Mila Kunis.

J Balvin; Howie Mandel; Jennifer Lawrence.

Julia Louis-Dreyfus; Drew Brees.

Kerry Washington; Brad Paisley; former first lady Michelle Obama and Ellen drive around Warner Bros. in a golf cart.

Sean "Diddy" Combs (CÎROC Vodka Spritz); Luke Bryan ("American Idol"); Chrissy Teigen and John Legend; Burbank, Calif., mayor Jess A. Talamantes.

Justin Timberlake; Keith Urban.

Kate McKinnon ("Saturday Night Live"); Ellen surprises the family of a U.S. Army first lieutenant who has been deployed for nine months in Kuwait.

Seth Meyers (book "I'm Not Scared, You're Scared"); Jerrod Carmichael ("Jerrod Carmichael: Rothaniel"); lifestyle expert Kym Douglas.

Rebel Wilson ("Senior Year"); John Paul DeJoria, co-founder of Paul Mitchell; viral stars Sophia Grace and Rosie.

Zac Efron ("Firestarter"); Ellen and OneRepublic's Ryan Tedder surprise a nurse who has been on the show five times; Bonnie Raitt performs.

Ellie Kemper; science guy Steve Spangler; Ellen welcomes back a man who broke his neck in a football game and became paralyzed, then committed himself to helping and inspiring others.

Diane Keaton (book "Saved"); Ellen welcomes back a couple who run a nonprofit that combats food insecurity on south side of Chicago.

Cynthia Erivo ("Roar"); a bookstore owner gives away books, gift cards, food and cash to neighbors in need; guest host Tiffany Haddish (movie "The Unbearable Weight of Massive Talent" and book "Layla, the Last Black Unicorn").

Jessica Biel ("Candy" and brand Kinderfarms); Behati Prinsloo (Tequila brand Calirosa).

Portia de Rossi; Ellen surprises a former guest; Dove Cameron performs.

Serena Williams (Serena Ventures); Jay Shetty; Indigo Girls perform.

Sterling K. Brown ("This Is Us," "Survivorship Today"); Nick and Vanessa Lachey ("The Ultimatum"); guest host tWitch surprises a high school principal who is a single mother of two and frequently pays out of pocket to provide for her students.

Lily Tomlin ("Grace and Frankie"); Ellen welcomes a young man and his mother, who offered him $1,800 to stay off social media until he turned 18; dancer Charlize Glass performs.

Robin Roberts (book "Brighter by the Day: Waking Up to New Hopes and Dreams"); Dwyane Wade (baby care company Proudly).

Jenna Dewan ("Come Dance With Me"); Jordan Davis performs; guest host Stephen "tWitch" Boss.

Katie Lowes ("How We Roll"); Tyler Cameron ("The Real Dirty Dancing"); magician Simon Pierro; guest host Mario Lopez.

Amy Schumer ("Life & Beth"); Tig Notaro (podcasts "Don't Ask Tig" and "Tig and Cheryl: True Story").

Former first lady Michelle Obama.

Anthony Anderson ("black-ish"); Kaitlyn Dever ("Dopesick"); MUNA performs.

Chrissy Metz ("This Is Us"); Christina Perri performs; guest host Mario Lopez ("Access") surprises a bride-to-be.

Joe Manganiello ("Metal Lords"); Simone Ashley ("Bridgerton"); guest host Tiffany Haddish ("The Unbearable Weight of Massive Talent," book "Layla, the Last Black Unicorn").

Tracee Ellis Ross ("black-ish"); Margaret Qualley ("Maid"); Brian Chesky, CEO of Airbnb; a memorable guest's daughter pays tribute to her.

Lena Waithe and Jacob Latimore ("The Chi"); guest host Kandi Burruss; Kandi's mother and two aunts cook; a cameo by a "Real Housewife"; Kandi surprises a special education teacher.

Wanda Sykes ("Netflix Is a Joke"); magician Blake Vogt; Alicia Keys performs.

Sarah Silverman ("The Sarah Silverman Podcast"); former NFL player Jon Dorenbos (book "Life Is Magic: My Inspiring Journey From Tragedy to Self-Discovery") performs a magic trick.

Allison Russell performs; guest host Brandi Carlile (book "Broken Horses: A Memoir").

Brené Brown ("Atlas of the Heart"); Sydney Sweeney ("Euphoria").

Laura Dern ("Jurassic World Dominion"); Ryan Seacrest ("American Idol"); Walker Scobell ("The Adam Project").

Lisa Kudrow ("Better Nate Than Never"); Ronda Rousey ("WrestleMania"); Blue Man Group ("Creature Feature") performs; dancer Dezi Saenz performs.

David Letterman; quick-change artist Léa Kyle ("America's Got Talent Las Vegas Live"); Ukrainian dancer Slavik "Vik" Vyacheslav Pustovoytov performs.

Guest host Leslie Jones; actor Samuel L. Jackson; Olympic gold medalist Chloe Kim.

Actor Channing Tatum.

TV host Mario López; a high school teacher working toward rebuilding his school band after COVID.

Actor Ted Danson; interview and performance by Kiesza; the founder of the Dovetail Project.

Actress Angela Bassett; actress Dina Shihabi; actress Alison Sweeney.

Guest host Stephen "tWitch" Boss. actor John Cho (Book, "Troublemaker"). actor Tyler James Williams ("Abbott Elementary").

Terry Crews ("America's Got Talent: Extreme"); Pauline Chalamet ("Sex Lives of College Girls"); guest host Julie Bowen (podcast "Quitters") welcomes a 10-year-old who can tell countless facts about different light bulbs and how they function.

Oliver Hudson ("The Cleaning Lady"); Lana Condor ("Moonshot"); a single mom whose passion is animal rescue; guest host Stephen "tWitch" Boss.

Machine Gun Kelly (album "Mainstream Sellout"); Mamoudou Athie ("Archive 81"); Ellen welcomes a 12-year-old who went viral on TikTok for his cover of "End of the Road" by Boyz II Men.

Russell Wilson (children's book "Why Not You?"); La La Anthony; guest host Ciara.

Singer Jimmie Allen; Priscilla Block performs; guest host Mickey Guyton welcomes a high school teacher who started a non-profit that provides nutrition for low-income students.

Kevin Nealon (book "I Exaggerate: My Brushes With Fame"); Jacob Elordi ("Euphoria"); Ellen welcomes a 7-year-old drummer.

Milo Ventimiglia ("This Is Us"); the founder of a fitness boot camp that hires formerly incarcerated individuals.

Colin Farrell ("The Batman," "After Yang"); Colman Domingo ("Euphoria," "In Five Speeches"); magician Mat Franco ("Magic Reinvented Nightly" in Las Vegas).

Greg Kinnear ("Shining Vale"); guest host Mario López ("Access Hollywood") welcomes a singer who shares vocal lessons on her social media.

Los Angeles Rams player and Super Bowl champion Andrew Whitworth; Marlee Matlin ("CODA"); a TikToker tells how she may have saved a customer's life after dropping off an Instacart order; Sylvan Esso performs.

Usher; child presidential expert.

Nicole Ari Parker ("And Just Like That ..."); a couple who run a camp to mentor kids and teach them to treat people with respect, love and kindness; guest host Stephen "tWitch" Boss.

Mark Wahlberg ("Uncharted"); Ellen welcomes back a high school principal who created an urban farm with the gift she gave him.

Hannah Waddingham ("Ted Lasso"); Kat Dennings ("Dollface"); beauty and lifestyle expert Kym Douglas.

Owen Wilson ("Marry Me"); Teddy Swims performs.

Kevin Hart ("Real Husbands of Hollywood").

Jennifer Lopez ("Marry Me").

Josh Gad ("Wolf Like Me"); mentalist Colin Cloud; Benson Boone performs.

Chelsea Handler; Scott Eastwood ("I Want You Back").

Sarah Hyland (vitamin line Sourse); UFC champion Julianna Peña; guest host Mario Lopez welcomes a part-time Uber driver who went viral for helping a passenger.

Halle Berry ("Moonfall" and "Bruised"); Sylvan Esso performs.

David Spade (podcast "Fly on the Wall"); Ellen welcomes the founder of a company that delivers fresh produce; Coldplay performs.

Murray Bartlett ("The White Lotus"); Ellen welcomes TikTok rappers.

Kristen Bell ("The Woman in the House Across the Street From the Girl in the Window"); Ellen welcomes back a 12-year-old who runs his own company and a nonprofit.

Guest host Brandi Carlile.

Paris Hilton ("Paris in Love"); head coach Vontae Johnson of the Trinity Valley Community College cheerleading team ("Cheer"); Lizzy McAlpine performs.

Courteney Cox; Chris Martin; Coldplay performs.

Ciara; Tabitha Brown (children's show "Tab Time"); Ellen welcomes 14-year-old twin violin prodigies who went viral.

Andrew Garfield ("Tick, Tick... Boom!" and "The Eyes of Tammy Faye"); Sherri Shepherd ("The Sex Lives of College Girls," podcast "Two Funny Mamas"); Ellen welcomes two college students who filmed themselves rescuing a dog from an avalanche.

Julianne Hough and Nina Dobrev (Fresh Vine Wine); guest host Adam Devine ("The Righteous Gemstones").

Mahershala Ali ("Swan Song"); Martha Stewart (website Martha.com); Ellen welcomes freestyle skier Colby Stevenson, who survived a near-fatal car crash, made a comeback, won the World Cup, and hopes to go to the 2022 Winter Olympics.

Coach Monica Aldama of the Navarro College cheerleading team ("Cheer"); KSDK news anchorwoman and reporter Michelle Li; aerialist Erin Blaire performs.

Steve Harvey ("Judge Steve Harvey"); freestyle rapper Harry Mack; Charlotte Day Wilson performs.

Heidi Klum; spoken word poet Brandon Leake ("America's Got Talent," book "Unraveling").

Adam Devine ("The Righteous Gemstones"); actress Julie Bowen.

Christina Ricci ("Yellowjackets"); past-life psychic Ainslie MacLeod.

Beth Behrs and Tichina Arnold ("The Neighborhood"); mentalist Oz Pearlman.

John Cena ("Peacemaker"); Ellen welcomes a woman who traded her way from a bobby pin to a house; Parquet Courts perform.

Jay Leno ("You Bet Your Life"); Black Pumas chat and perform.

Nicole Byer ("Grand Crew"); guest host Stephen "tWitch" Boss surprises a former social worker who opened a low-income school on the south side of Chicago.

Penélope Cruz ("The 355"); shark expert Demian Chapman ("Endangered" campaign).

Jessica Chastain ("The 355"); Ellen welcomes a 7-year-old whose speech has gone viral; "The Voice" season 21 winner Girl Named Tom performs.

Lily Collins ("Emily in Paris"); science guy Steve Spangler; The War on Drugs, ft. Lucius, performs.

RuPaul ("RuPaul's Drag Race"); an interview and cooking demo with chef José Andrés; Jim and Sasha Allen ("The Voice").