Fillmore-Graves prepares to execute Liv and Levon, while Ravi, Liv, and Peyton try to organize a rebellion. Meanwhile, Angus leads his followers against the U.S. Army encircling Seattle.

Major abducts Liv‒but in a nice way‒so Ravi helps Clive with a case. Meanwhile, Blaine tries to convince his father to take his preachings nationwide, and Ravi makes a breakthrough with his anti-zombie vaccine.

Angus' church continues to grow in power and influence with the zombie community, while Clive and Liv investigate the murder of a man posing as a woman. Meanwhile, Major meets with the head of the braintube-skimming operation, and Chase loses it.

While Liv continues leading the human smuggling underground, Ravi agrees to act as father to Isobel while trying to find a zombie vaccine.

While Blaine begins a new scheme to make money from the zombie cure, the city goes into lockdown when a serial killer escapes. Liv, Ravi, Peyton, and Clive are trapped in the station and make the best of it, while Major tries to find the killer.

While Clive and Liv try to determine how a medieval LARPer died, Stacey returns to Seattle to find a stash of money... unaware that Petyon has it.

To solve the murder of a wingman-for-hire, Liv eats his brain and starts hitting on everyone in sight. Meanwhile, Clive tests his open relationship with Dale, and Chase orders Major to get close to Russ.

Liv sets out to take on Mama Leone's role smuggling humans into Seattle, and her newfound acting talents after eating a theater actor's brains prove invaluable. Meanwhile, Ravi eats a heroin addict's brain to help Liv, and Angus finally pays Blaine a visit.

Clive and Liv track the murder of a hockey player, and discover that he was connected to Renegade's human-smuggling operation... and that Blaine killed him. Meanwhile, Peyton discovers first-hand that the brain-tube supply is decreasing, and Major and Don E abduct a young girl.

Olivia and Clive enlist Ravi to help them trap the coyote serial killer. Meanwhile, Blaine eats the brain of an honest man to learn Renegade's whereabouts, and Major enters dangerous territory meets a familiar face.

Liv's newest brain is a helpless romantic who was killed while trying to find her soulmate in Seattle. The trail leads to a vicious coyote who is less than trustworthy. Meanwhile, Fillmore Graves faces a brain shortage and Chase goes to Blaine for help.

Olivia eats the brain of a murdered dowager and becomes just as obnoxious as she and Clive try to figure out who murdered the woman. Meanwhile, Clive tries to figure a way around his intimacy issues with Dale, and Major has to choose between his friends and his duty when he discovers they're smuggling humans out of Seattle.

In New Seattle, a Seahawks superfan is killed and Liv eats his brain to find out who is responsible. Meanwhile, Ravi deals with the side effects of the vaccine and Angus escapes from the well.