With her father's help, Natalia reunites with Ahillea, and the couple decides to settle in Thessaloniki. Nikiforos is devastated by this decision and loses his sense of fun. Xanthippi gets back with Mimis, who is determined to abandon the crazy antics of the past and dedicate himself to his family. On the contrary, Pavlos meets Maria-Eirini's equally hot roommate. The gang decides to take a vacation for a last adventure. So do the girls who want to join Eirini on her travels. But fate has other plans.

Xanthippi leaves without notice and goes to London to meet Eirini, and Mimis goes crazy. Pavlos struggles with loneliness until he meets an attractive neighbour. Nikiforos invites for dinner Giorgos, Natalia's college crush but Ahilleas, who knows everything, makes a scene and abandons Natalia. Now, it's time for Nikiforos to make things right.

The three guys are shocked after they catch Elisavet and Xanthippi watching a male stripper in Mimis' house. Mimis asks bitterly for a divorce from Xanthippi. At the nursing home, Pavlos has to deal with Elena's advances, while an encounter with an old acquaintance gives Nikiforos the opportunity to hatch a risky plan with multiple benefits.

The three friends get a 90-hour penal labour sentence. They serve in a nursing home under a strict supervisor, and they'll have to use their wits to survive the chores. In the meantime, Elisavet and Xanthippi worry about Eirin, who is not answering their calls. Eva lets them know that they'll hear from her soon. Eirini sends a letter in a very peculiar way, explaining the events after the passionate kiss she shared with Pavlos and her subsequent decision.

The three men prepare for the trial of the hostage situation at the tavern several years ago. But the trio, with their antics cause mayhem in the court. They get long-term sentences in a prison farm. After three years, they receive letters with bad news from their wives, and they decide to escape. But our heroes have seriously sinned by breaking the Ten Commandments, and only a divine intervention can change their fate.

Nikiforos becomes an ascetic stylite as a reaction to the contempt from his family. Mimis uses Confucian philosophy to deal with a watchdogging Xanthippi and the fact that Kimon, Vivian and Panagiotakis are moving out. Maria dumps Pavlos, and he calls over his friends for support. At the same time, Eva comes back home with her modern ideas and offers some advice to her father, inciting him to a daring act.

Nikiforos, Mimis and Pavlos will have to face the consequences of their actions. They get the cold shoulder at home. But things are worse for Pavlos since Maria is seeing Traianos. Humiliated and desperate, the three friends now must think of a way to fight back.

Everybody is upset since Panagiotakis ran away from school and is missing. The guys have to stop flirting with girls and help find the boy. While searching, Mimis accidentally sees Maria kissing Traianos. Finally, the boy is found, and Mimis decides to go back to normality. Maria confesses to the girls that she watched Pavlos and witnessed his date with Nikoleta. But Nikiforo's romance with Tzortzina will not be a secret for long, as well.

The relationship between husbands and wives is at its worst point. Mimis gets back to the factory to take over and relieve Vivian, and he notices Kimon's beautiful secretary. Pavlos also flirts with his son's kindergarten teacher. Nikiforos meets a single mother at the playground, while Elisavet accepts the romantic advances of a foreign partner.

The girls fake Maria's death and let the guys believe that they will be suspected of murder. Desperate Pavlos and his friends hide in an abandoned TV studio. Elisavet makes sure that they will suffer as long as possible. The scheme will be revealed only after they decide to surrender. Their revenge plan includes breaking another commandment.

The three guys hide themselves in a luxury hotel in order to avoid the wrath of the women. Elisavet bumps into them by chance, and the girls exact their revenge by humiliating them. Nikiforos attends to Natalia's and Ahilleas' problem. Vivian gets pregnant. The gang conceives a plan to intimidate the women.

The women decide to play along, and it's their turn to play the seduction game. At first, the guys got surprised, but they'll rebound, pushing the limits of everybody involved. At the end of the day, Elisavet, Eirini and Xanthippi find themselves trapped in a ship's hold.

To take revenge, the three friends decide to break the Ten Commandments, and they start with 'Thou shalt not covet'. Overconfident, the trio sets out to seduce each other's wives but with very poor results. Ahilleas and Natalia arrive from the US, and it seems something's wrong between them.

The road trip ends before it even begins. The wives find out, the guys have a car crash, and end up injured. They make up new lies to justify the trip but they can't outsmart the women, at least not all of them. Elisavet hatches a fiendish plot to divide the male company through malicious gossip. Before the three friends understand what is going on, they'll quarrel with each other.

After the events at the tavern, Vasilis has banned the three friends from his place. Finally, they'll find a way to change Vasilis' mind, and they'll be back to the glory days. Of course, the women are not going to accept it and threaten them. The male gang decides to take a road trip to Tyrnavos for a tsipouro festival. They will have to find different excuses to get away from their wives, but it will not take long before their plan gets exposed.