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The hunt for Pablo seems to be over once he signs a deal with the government, but Murphy, Peña and the Calicartel have different thoughts about that.
A tragic mistake forces the government to change strategies to fight Pablo, but Pablo has bigger issues as there is danger from within his empire.
Pablo's activities in prison forces the government to use extreme actions. Murphy and Peña have to deal with a problematic situation.
As drug lord Pablo Escobar rises, Colombian and U.S. law enforcement find themselves battling an enemy who will do anything to keep his empire.