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When the latest heir to the Baskerville estate seems to be threatened by a family curse, only the master detective, Sherlock Holmes, can find out the truth.
Sherlock's brother, Mycroft, enlists his younger sibling to locate missing patent plans that pertain to a strategically critical state-of-the-art submarine.
A bored Holmes eagerly accepts a case involving the disappearance of an amateur Spanish cartographer, as well as his servants, from his rented country lodge.
Holmes investigates the disappearance of a champion racehorse and the murder of its trainer on a lonely moor.
While convalescing in Cornwall, a depressive Holmes investigates the apparent death from apoplexy of a local woman and the unexplained sudden dementia of her two brothers.
The disappearance of a young woman's father, and a mysterious note years later after the strange regular annual delivery of valuable pearls to her, puts Sherlock Holmes on the case.
Inspector Lastrade reveals to Holmes that someone has been breaking into homes for the senseless purpose of destroying small busts of Napoleon.
The headmaster of a prestigious prep school calls on Holmes for help when the ten year old only son of powerful duke disappears.
Responding to a grieving wife, Holmes investigates the apparent murder of her husband in an apartment above an opium den.
Holmes is asked by the country's Prime Minister to aid in the recovery of a stolen diplomatic letter, which, if published, might lead England into war.
An obscure family document containing an enigmatic ritual holds the key to a hidden treasure if Holmes can decipher the mystery.
Holmes is called to a manor house to investigate the brutal murder of a country lord with a fireplace poker, and reconcile the story of his bruised and battered wife with the facts.
Believed dead after his fatal encounter with Professor Moriarity three years earlier, Sherlock Holmes returns to England to foil a plot to murder him by a former Moriarity gang member.