Connie is forced to choose between her addiction and her career, Duffy has a hard day and finds herself back in the ED, and Iain takes new emergency care assistant Siobhan under his wing.

When David sees that Charlie is struggling to cope, he intervenes and tries to remind Charlie that he is not alone. Meanwhile, Marty's mother is rushed into the emergency department, and he and Jade have to keep up the pretence of being boyfriend and girlfriend in front of his family. Elsewhere, Connie continues to cover her tracks.

Reliving the events of the previous day and unable to escape her own guilt, Connie schemes to save herself by planting a seed of doubt in Duffy's mind. Meanwhile, New porter Rosa makes quite the first impression in the emergency department. As she goes beyond the requirements of her role and gets involved with the patients, David thinks she is overstepping the mark.

Connie takes the opportunity to prove herself, but it ends in disaster. Duffy proves her worth in the ED but gets caught up in Connie's mistake, and after a tough day, Iain plucks up the courage to talk about how he's feeling and realises just how far he's come.

Iain gets embroiled in a tricky case with a familiar face, while Jade gets more than she bargained for with Marty.

Jacob makes peace with Omo when he honours her final plea and takes her home from the hospital, where she can pass away peacefully in the comfort of her own bed. Elsewhere, Archie confides in Will that it was Connie who made the mistake with a patient, not her. Later, Adam is rushed to Resus where Will treats him, and Sofie is riddled with guilt.

Jacob discovers a truth about his past when he finds out his father may still be alive. Meanwhile, Duffy decides that it is time for her to step down as an emergency department nurse, and Connie is furious with Ciaran when she finds out that Duffy has stepped down. Elsewhere, Jade learns of Marty's betrayal.

Connie continues her downward spiral, while Jacob pulls the wool from his mother's eyes.

Ruby finally plucks up the courage to admit her mistakes to the rest of the team, and Iain offers her his support. Ciaran is tested by his colleagues when he is left to run the department on his own for the day, and Jade starts to believe in herself. Meanwhile, Archie and Will bond as they make fun of Ciaran's productivity charts.

Iain steps up and offers his support to Jan. Trouble shooter Ciaran arrives in the Emergency Department. With just three months to turn things around, he is determined to shake things up, much to Connie's dismay. Meanwhile, Jacob decides to confront Jet in an effort to fight for his mother's wellbeing.

Elle learns the truth about her new job. Meanwhile, Jacob makes a shocking discovery about his mother, and Ruby continues to hide the truth from Dani and her team.

Will and Archie put aside their differences when Toby is rushed into the ED. Will is torn between Toby's wishes and those of his mother, who wants to try every treatment available.

Iain goes above and beyond on his first day back as a paramedic, and Duffy starts to doubt whether she should have been so open about her diagnosis.

Feeling like he is not quite ready to return to work as a paramedic whilst on his road to recovery, Iain takes on a new challenge as a 999 call handler.

Charlie begins to realise how much he has let Duffy down, Rash decides to follow his dream to go travelling, and Elle is offered an interview for a job at another hospital.

Connie comes face to face with her attacker in the ED, and Duffy finally comes clean about her dementia diagnosis. Ruby starts to get uncomfortable when Dani keeps turning up out of the blue, Jan and Ruby discuss Iain's return, and Jade's nursing registration comes through.

Charlie snaps under the pressure of keeping Duffy's ill health a secret, and Rash puts aside his dreams of travelling the world to stick by Gem.

Archie butts heads with charming paediatric locum registrar Will Noble when they meet in the car park. Will reconnects with old friend Ethan and ingratiates himself with the staff.

The aftermath of Iain's attempted suicide ripples its way through the emergency department. Meanwhile, wracked with guilt, Ruby goes out of her way for a patient.

A cyber-attack rocks Holby hospital and has a devastating impact across several departments. Meanwhile, Iain's life hangs in the balance.

Marty plays counsellor for a couple having problems with their relationship, and after a busy and fulfilling day, Iain feels that his work with Ruby is done.

Iain reaches out to someone from his past, but he does not get the response he was hoping for. Meanwhile, Marty and Jade learn to work together.

Louise pulls out all the stops to get Ernest his surgery, but will it be enough to save his life? Connie alienates the team just when she needs them the most.

Iain faces time behind bars for attacking Ross. Will anyone believe his version of events? Ethan starts to move on from Alicia, and Louise vows to protect her nurses.

Iain walks into the firing line to protect his team. Will he be able to talk the gunman down? Meanwhile, Louise kicks up a fuss to save Ernest.

Alicia gets a coveted fellowship in Manchester. Will she choose Ethan or her career? Meanwhile, Marty's lies come back to bite him.

Alicia saves a baby, and the reality of Duffy's diagnosis starts to sink in.

Iain gets beaten up, and Marty chooses his career over friendship with Jade.

Dylan faces a traumatic Christmas in Resus. Noel is delighted to have met his Christmas fundraising goal, but can't quite decide on a charity to give the money to.

Tension runs high when Bill is admitted to the ED - will Charlie find out about Duffy's affair? Alicia learns to trust her instincts.

After a hard day, Iain seeks comfort in the wrong place. Duffy makes a shocking diagnosis.

It's crunch time for Dylan and Ciara, while Jade and Marty start to get along.

Dylan and Ciara make their escape. Will they finally get their happily ever after?

Louise takes a chance on a young nurse, and Iain finally reaches out for help.

Duffy wakes to find she has made a huge mistake. Is Iain really coping as well as he claims?

It is judgement day for the ED, as the inspectors descend. Dylan has to face Ciara. Louise's management style frustrates the nursing team.

Zsa Zsa returns to save Dylan, but can even she help him? Rash reels from his break-up with Gem.

Jacob is faced with his past. Will Iain's heroics stop him spiralling out of control?

Ruby and Iain are together for a shift, neither keen on the idea, and it gets worse when they find out they've been pranked by kids. A pregnant woman is involved in a car crash, and Duffy confides in an old flame.

When Ciara comes into the hospital, Dylan faces a personal tragedy. Will he be able to stay on the wagon? Iain secures Base a place in rehab. Blake hears an anecdote about Jacob's mother Omo and becomes determined to find her.

David and Ciara fight over Dylan - who will he choose? Iain returns to work, trying to make up for Mia's death.

Tensions run high on the day of Sam's funeral, as a grieving Iain faces his tribunal hearing.

After recent traumatic events, how will Alicia cope with returning to work earlier than expected?

Ciara comes back into Dylan's life, while the fallout from the crash affects the whole department.

Iain's mistake with a patient has serious repercussions, putting many lives in danger.