Based on the "creepypasta" short story Hidden Door, Channel Zero: The Dream Door follows newlyweds Jillian and Tom, who have each brought secrets into their marriage. When they discover a strange door in their basement, those secrets start to threaten their relationship — and their lives.

Butcher's Block, the third installment of the Channel Zero anthology series introduces us to Alice Woods and her schizophrenic sister Zoe who have moved to a small town to start over. Alice lives in constant fear of inheriting Zoe's illness. On the outskirts of town lies Butcher's Block, a hellish neighborhood where junkies roam and lawlessness abounds. It is here the sisters encounter Joseph Peach and his eerily charismatic family. The Peach's are not your ordinary family; they live above the Butcher's Block in a dimension that is dark utopia. They offer the sisters a place at their table with promise of a world without worry and without illness. The sisters soon find that the cost of living the good life comes at an unimaginable price and there is a fine line between escaping insanity and embracing true madness.

Inspired by Brian Russell's Creepypasta tale, Channel Zero: No-End House tells the story of a young woman named Margot Sleator who visits the No-End House, a bizarre house of horrors that consists of a series of increasingly disturbing rooms. When she returns home, Margot realizes everything has changed.