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Alex flees the practice and heads back home to York, hotly pursued by Tom, who tries to persuade her to face up to her illness.
Tom is caught in a dilemma when a harassed mother requests an abortion without telling her husband. Alex faces her cancer test ordeal alone.
Will's career is thrown into turmoil when one of his patients has an epileptic fit while driving and is killed in the ensuing crash.
Alex struggles to save a boy's life after a farmer dumps dangerous chemicals in a pond, but is distracted when her estranged father turns up seeking a reconciliation.
Tom helps a swimming instructor come to terms with a serious bowel condition, and a meals-on-wheels driver suffers a stroke at the wheel and nearly crashes into Kate.
Will unwittingly brings to light a family scandal, while Tom and Alex's budding relationship is jeopardised by a difference of medical opinion.
The Mayor of Cardale suffers severe attacks of lethargy, and Tom uncovers an affair between a local teacher and her pupil.
Will treats a nun with a broken arm and in the process finds she's dying from an incurable illness, a traumatic revelation that brings him closer to wife Kate.
Alex helps two elderly sisters against Will's orders and discovers something about herself into the bargain, wjile Tom persuades Kerri to face everyone at work.
Will uncovers the extent of Sam's deception as he prepares to go down the aisle with Kerri, leaving the bride with a tough decision to make.
Tom fears cyclist Nick Pullen is being pushed beyond his limits by an overzealous trainer, while Will clashes with ex-wife Kate over an alcoholic patient.
Tom blows his top when Bridgit breaks the rules by having an affair with a haemophiliac patient, and Sam invests in a controversial new drug.
Will's sympathy for a couple of old friends contemplating fertility treatment soon turns to irritation when they opt to take matters into their own hands.