Miami visits Las Vegas. The Dolphins enter this match two games up on the Raiders for the final wild-card spot in the AFC, with Las Vegas needing a victory to keep its playoff hopes alive. Miami rushed for 250 yards in a Week 15 win over New England.

Tampa Bay (9-5) visits Detroit (5-9). The Buccaneers engineered a comeback of epic proportions in Week 15 after knocking off the Falcons 31-27. Antonio Brown caught his first TD pass as a Buccaneer as part of a 31-point second half from Tampa.

The Saints (10-4) can claim their fourth NFC South title in a row with a victory over the Vikings (6-8). New Orleans lost to Minnesota in two of the last three postseasons. The Saints have dropped two straight games since clinching a playoff berth.

The Ravens host the Cowboys in a game originally scheduled for Dec. 3. Dallas has not played since Thanksgiving, a 41-16 loss to Washington. Baltimore and Pittsburgh were to meet on Thanksgiving, but that showdown was postponed until Dec. 2.

The top teams in the AFC South clash as the Titans (6-2) host the Colts (5-3). Tennessee snapped a two-game slide and is off to its best eight-game start since 2008 with a 24-17 win over Chicago last week. Indianapolis was stymied 24-10 by Baltimore.

The Packers visit the 49ers. San Francisco advanced to Super Bowl 54 after a 37-20 win over Green Bay in last season's NFC Championship Game. Niners stars Jimmy Garoppolo and George Kittle will each miss multiple weeks with ankle and foot injuries.

The Falcons try to bounce back from a devastating loss when they visit the Panthers. Atlanta fell to Detroit 23-22 last week on a touchdown with no time remaining. Carolina snapped a five-game series slide with a 23-16 victory at Atlanta in Week 5.

Patrick Mahomes and the Chiefs match wits with Josh Allen and the Bills. Mahomes watched from the bench while Allen was still at Wyoming when Buffalo ended a three-game series slide with a 16-10 victory over Kansas City in 2017 in the last meeting.

The Broncos head into the Garden State for a conference matchup against the Jets. In their last meeting in 2018, New York ended a three-game slide against Denver with a 34-16 victory. Sam Darnold (NYJ) threw three TD passes in that triumph.

Miami (0-2) visits Jacksonville (1-1). Gardner Minshew and the Jaguars nearly engineered their second upset of the season in Week 2, but lost to the Titans 33-30. Minshew is tied for the lead in the AFC with six TD passes entering this game.