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Mannix and the police bust up a drug ring, but a dealer escapes and takes six people hostage to force the authorities to hand over the man who betrayed them to the cops.
A hit man kills a mob boss but the body disappears, so the killer hires Mannix to find the dead man.
A newspaper publisher hires Mannix to acquire evidence that his wife Rebekah is having an affair and convince her to break it off. But after Mannix does so, he suspects that the entire thing was a set-up.
Mannix goes on the run after he's framed for the murder of a country's president.
Mannix travels to a tropical island country to take a case to find a man, but is soon embroiled in a plot to kill the country's president.
A hitchhiker Mannnix picks up is accused of murder, and the PI tries to clear the man's name.
Mannix and a friend are locked in an office building by three thieves looting the place.
A kidnapper demands a ransom from his victim's mother... six years after the boy was kidnapped.
A former student is accused of killing his former professor, and hires Mannix to find the real killer.
An Army deserter kills Peggy's cousin's husband, and Mannix tracks down the man responsible.
An older PI is shot while working a case, and the man's wife asks Mannix to find the shooter.
A former soldier who broke under torture and who Mannix helped court-martial set out to get revenge on the PI by putting him through the same ordeal.
A wife hires Mannix to discover who killed her husband during a charity show rehearsal... when she may have been the target.
The survivor of a plane crash undergoes plastic surgery, and his wife hires Mannix to find out if he's really her husband.
Mannix looks into an Indian's death in a small New Mexico town ruled by fear, intimidation, and prejudice.
Mannix is hired to look into the death of one photographer and gets romantically involved with another.
A Japanese PI comes to Mannix looking for help tracking down a missing Japanese courier.
While investigating the death of an old friend from the Korean War, Mannix discovers that someone claiming to be him has been living in San Francisco for the last three weeks while Mannix was on a fishing trip.
Mannix investigates anonymous death threats against him that turn serious when someone takes a shot at him.
Mannix joins in the search for a missing counterfeiter with plates that both the Feds and the mob want.
The Syndicate abducts Peggy, mistakenly believing that she's an informant against them, and Mannix goes all-out to find her.
A girl comes out of a coma after a year, but finds that her problems are only beginning when unknown killers try to take her life.
Mannix comes to Albuquerque to help his goddaughter.
Mannix looks into the near-death of a musician who was almost electrocuted while performing on stage.