Mannix turns up missing after 17 days, hooked on heroin by a brother seeking revenge.

A mobster hires Mannix to find a stolen package for him.

A young boy asks Mannix to investigate the death of his hero: a boxer killed in a hit-and-run.

A cop accused of murder asks Mannix to help clear his name, even though multiple witnesses swear the cop was responsible.

A psychiatrist apparently kills himself, but the wife suspects one of his clients is responsible.

Mannix tries to identify a little girl who was killed when a parade stand collapsed. No one can identify the body, but someone anonymously sends $500 for the girl's burial.

Mannix tries to clear a client who is accused of murder in a locked-room mystery where no one else could have killed the victim.

Mannix's friend Lt. Malcolm takes a double blow when he's framed for the murder of his fiance.

After an attack leaves Mannix near death, he tries to solve the case from his hospital bed while recovering from his injuries.

Mannix and Carradine try to save Victor, but a traitor in the rebel camp threatens their efforts.

A client hires Mannix to smuggle heart surgeon Dr. Myles Considine into a dictatorially-run country to operate on a revolutionary.

The survivors of an airplane crash are murdered one by one.

Mannix runs into an old girlfriend while in San Francisco to wrap up a case, and soon gets involved in a financial scam for $14 million.

An actress trying to make a comeback after a year in a mental sanitarium hires Mannix to find how who is trying to drive her insane.

A blind crook will do anything to get his hands on a priceless diamond collection.

Mannix becomes romantically involved with a client: an opera singer who plans to go on despite two attempts on her life.

A mobster sends a hitman after his former girlfriend when she links up with an ex-quarterback, and Mannix steps in to protect them.

Mannix falls in with bad company when he stumbles across a murder-for-hire ring during a fishing trip.

Mannix discovers that a small town hides a big secret when he's hired to find the pilot of a crashed airplane.

Mannix faces off against a street gang after he's forced to kill a former member in a shootout.

Tina Reynolds witnesses her father Lou's murder at the hands of a hitman at a zoo, and claims that she's responsible.

Mannix's plane is hit by lightning and goes down in the mountains. Escaped convict Luke Whitney rescues him, but three prison guards on Luke's trail want them both dead.

Mannix travels to a hostile small town to look for a teenager on trial for murder and released on a technicality, who subsequently disappeared.