Season Four opens with the team unexpectedly traveling to the future to find an unwelcome surprise. Faced with their imminent demise, the Doom Patrol must decide once and for all which is more important: their own happiness or the fate of the world?

DC's strangest group of heroes are back again to save the world. That is, if they can find a way to grow up…both figuratively and literally. Following the defeat of Mr. Nobody, the members of the Doom Patrol now find themselves mini-sized and stranded on Cliff's toy race car track. Here they begin to deal with their feelings of betrayal by Niles Caulder aka The Chief, while confronting their own personal baggage. And as each member faces the challenge of growing beyond their own past traumatic experiences, they must come together to embrace and protect the newest member of the family: Dorothy Spinner, Niles' daughter, whose powers remain a mysterious but real threat to bringing on the end of the world.