A man plans to brainwash his wealthy sister (Kerrie Keane) into signing their father's estate over to him.

CJ is holidaying at a beach club when a guest is mysteriously murdered. She asks Matt to help the club owner solve the murder, which is the second one to happen. A detective (Deborah Adair) has a personal stake in Houston's murder extortion case: one of the victims was her sister.

A killer (Judson Scott) Houston put behind bars is freed on a technicality and tells Houston (Lee Horsley) that he's going to kill him

Matt's only suspect (James Read) in the murder of a fashion model and her chauffeur has a seemingly airtight alibi. 

A Vietnamese warlord captures Matt and holds him for ransom after Matt is double-crossed by a soldier of fortune (Max Baer). (Part 2 of 2).

Despite disapproval from the federal government, Matt plans to rescue his cousin (Michael Goodwin) after learning the man is alive in a Vietnamese prison. (Part 1 of 2)

Stricken with amnesia after a car accident, C.J. (Pamela Hensley) lands in a women's prison where inmates are forced to work for politicians. 

Matt wants to know if young Peg Allyson has been coerced into joining a religious cult, but before he can check out the evidence, C.J. is gravely wounded by one of the cult leader's disciples.

C.J falls in love with Robert Tyler, an old school chum who is now a television anchorman, and Houston thinks that Tyler is in cahoots with a gang of kidnappers. 

A killer kidnaps Hoyt's daughter, but when Hoyt and Houston nail a suspect, they learn that their Illegal tactics may set him free.

Falsely accused of two murders, fugitive Matt Houston (Lee Horsley) turns to his uncle (Buddy Ebsen), a retired criminologist, to help pin down the real killer (Andrew Prine).