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On the season 4 finale, Charlie's condition proves more dangerous than initially thought, as Alex and Shahir struggle to save his life.
After Kristine suffers a stroke, Alex discovers the nurse's past may not be as she remembers, so Alex teams up with Charlie to find a way to bring peace to the already troubled spirit.
Alex and Cassie try to free a young woman from her abusive partner; a patient's pacemaker malfunctions.
Charlie decides to go a day without using his special abilities. Alex organizes a trip to Dana's cabin. Zach takes control of a life and death situation involving Dawn's college roommate.
Alex and Jeremy struggle to find the truth when all the symptoms of a permanently ill child point towards his mother as the cause.
Alex must maintain her professionalism when Kristine lands at Hope Zion Hospital after a drunk-driving accident with baby Luke's blanket.
With Dana back from Paris, Alex enlists her help to save Lorenzo, a hot-tempered chef suffering from oral cancer. Her concerns over her friend's own treatment (or lack there-of) quickly bubble to surface however, when their patient refuses medical attention in favour of pursuing the opening of his restaurant. Meanwhile, Charlie has his hands full juggling the spirit of a restless single mother, while working to save her life after a DIY treehouse accident.
When an ice storm strikes the city, Alex and Dawn struggle to keep a good Samaritan alive long enough for her family to say goodbye.
Alex is distraught when she learns that she unknowingly helped the bomber at the expense of a friend.
A bomb explodes during a charity run and the majority of victims are brought to Hope Zion Hospital, including some staff.
The death of a trapeze artist sets off a transplant chain of donors & recipients, leading Alex & Shahir to juggle complications & patients.
When an aggressive brain tumor threatens the life of her patient, Alex must convince Shahir to use an equally aggressive treatment.
Dr. Alex Reid must decide whether or not to use information Dr. Charlie Harris gets from a patient's spirit in order to save their life.
A motocross rider is diagnosed with Leukemia, forcing Alex to navigate family secrets in order to put her patient on the road to recovery.
Worried about the lack of family in her baby Luke's life, Dr. Alex Reid gets more than she bargained for.
Dr. Alex Reid has to juggle her duties as a new mother and a surgeon when she takes a Junior Resident under her wing.
Dr. Alex Reid puts her reputation on the line when she questions a senior surgeon's methods.
On her first day back from maternity leave, Dr. Alex Reid (Erica Durance) has her hands full when a new mother comes in following a car accident.