Two detectives deal with the loss of a friend and a husband, and are assigned to work under a new team. J. C. and Nina are assigned to work under Lt. Malcolm Baker, played by Thomas Mikal Ford, and with their new partners, Detective Alec Stone, played by Josh Hopkins, and Detective Nell Delaney, played by Marisa Ryan. J.C. is coping with Eddie's death and is trying to help his son, "G", grow up to be a man. Nina is trying to survive being a widow and concentrating on being a good detective. As time passes, the two start to form an attraction for each other, which leads to something they both never thought possible. Detective Alec Stone is cocky cop who does what he can to get the job done. Detective Nell Delaney is a tough cop whose smart comments and intelligence keeps her ahead in the game. Finally, we meet Lt. Malcolm Barker, a ferocious cop who knows what he's doing and doesn't let anyone stop him in the actions he makes.

A new detective joins the crew, a relationship heads to a new road, and death takes its ugly toll on two of the detectives. Jonathan LaPaglia joins the cast as Detective Tommy MacNamara, an Irish cop with a know-it-all attitude and a distinctive personality, which doesn't go well with the team, especially J.C. Unfortunately, he was only able to shine his talents for a short while due to his murder. Eddie and Nina go through many obstacles in their relationship, especially when Nina is trying to recover from a gun shot wound she got last season. Eddie is determined to make it last and asks Nina to marry him, which she accepts. However, in order to make that happen, Nina must divorce her first husband. Nina is also going through the process of trying to get her daughter, whom she gave up for adoption, back into her life. While dealing with that, for a while she starts to question her future as a cop. While Eddie is learning of these new secrets about Nina, he deals with his father's death (or suicide), and unfortunately meets an untimely death. As for Lt. Cooper, she starts an elicit affair with a captain and goes through a rocky separation from her husband and family.

A new character has joined the team. Detective Nina Moreno, played by Lauren Velez, is a young Puerto Rican who was introduced as Eddie's new partner due to J. C. being in the hospital because of his close encounter with death. As she struggles to be a good cop, she also tries to earn respect from Eddie. As for J.C., he is recovering from his wounds caused by his enemy who also killed Sandy. J.C. once again finds himself struggling to put his life back together and dealing with the loss of Sandy, and can only relieve his pain by getting back on the streets. For Eddie, he tries to get his friendship back with a distant J.C., he is fighting his feelings for Nina, and helps his father who is dying of AIDS.