Banner gets involved in a war for control of dockworkers union in Galveston, Texas.

Looking to gain access to some sophisticated gamma radiation equipment at a nuclear power plant in California, David forges some paperwork to pass himself off as a nuclear plant inspector. However, while he's there, an earthquake happens and causes so much damage that only David – in the form of the Hulk – will be able to fix.

On his way to volunteer for a questionable and possibly dangerous experiment that could help him get rid of the Hulk, David crosses paths with a young, pregnant woman. They soon find their lives in danger when the doctor in charge of the experiment runs an illegal baby selling operation and set out to kill David and the girl in order to keep the business under wraps.

While hitchhiking, David gets picked up by a woman truck driver. When she shares with him her intent to get her father's tanker truck back from the highwaymen who stole it, he tries to talk her out of following through with her plan. When that doesn't work, he takes it upon himself to help her out.

While working in a casino, David helps a Las Vegas reporter with a gambling scandal, only to discover that the reporter is Jack McGee's partner.

David boards a flight to visit another doctor whom he thinks has information that might help him with his problem. But, when the pilot and stewardess drugs the rest of the crew in an attempt to bail out of the airplane with stolen property, David and a young boy named Kevin try to land the jetliner.

David discovers a murder plot while working in a Time Square arcade, where the owner is being extorted to pay for protection.

After a transformation as the Hulk, David awakens in a room with a dead model and fears he may have killed her.

While working at a zoo, David finds a female scientist doing genetic research, which could help him stop his unwanted transformations into the Hulk.

After a boxer named Rocky rescues David from muggers, Rocky gets David a job at his gym. David tries to help Rocky when he discovers that their boss is a drug dealer and using the unknowing Rocky to deliver the goods.

With the world believing him to be dead, David Banner is on the run, trying to find a way to be cured of his transformations into the Hulk. Meanwhile, David lands a job at a ranch, where he befriends a young heiress. He notices that the woman is being given a questionable drug by her physician. He then overhears a plot to kill her so that her stepmother could gain an inheritance; he also learns that the recent death of the young woman's father was no accident. Now, David must get the heiress to safety before it is too late.

An accidental overdose of gamma radiation creates a mutation in David Banner's DNA, and, whenever he becomes angry, it causes him to metamorphose into a seven foot, 338-pound, green hulking creature. A reporter, Jack McGee, begins investigating claims of a giant monster; his investigation leads to Banner's laboratory. An explosion in the lab kills friend Elaina Marks; McGee, who dubs the creature "the Hulk", believes the Hulk killed David too. Unable to explain the truth, nor control his transformations, David leaves to try and find a cure for himself.