Dr. Jeff and his team continue their work through the chaos of the COVID-19 pandemic. A beloved dog is hit by a car and needs surgery to save its leg, and a cherished cat is rushed in with a mysterious bleed. A puppy is suspected of eating DVDs.

Dr. Jeff helps a puppy with a mysterious and painful injury; Shelter volunteers drive from Kansas hoping Dr. Jeff's team can save a tiny rescued dog hit by a car; the team travels to Tennessee to help Jeff's cousin provide free vet care.

A celebration of Dr. Jeff's 30-year career helping pets around the world; a behind-the-scenes look at the clinic where Dr. Jeff and his team remember some of their favorite stories.

Dr. Jeff treats a couple's cherished bloodhound puppy that won't eat. Dr. Petra races to save a cat after he's swallowed a handful of hair ties. And Dr. Jeff and Hector head out to a veteran's ranch to help a baby therapy yak.

Dr. Jeff and his team head to a remote town to provide low-cost pet care; Dr. Petra performs life-saving surgery on a basset hound hit by a car; a cat with plenty of attitude needs Dr. Amy to treat his mysterious wound.

Dr. Jeff returns from a free vet care clinic with a dog who was hit by a car; the owner of a kitten with suspected ringworm gets more than she bargained for; Dr. Jeff treats a family dog with a mysterious lump; Dr. Baier falls for a rescued puppy.

Dr. Jeff helps a beloved German Shepherd walk again; the team tries to rescue a scared dog on the loose outside the clinic; Dr. Don must move fast when a family cat eats poison; Dr. Jeff and Hector head for the mountains to help two rescued camels.

Dr. Jeff and Hector help 40 miniature Australian shepherds rescued from a puppy mill; Vet tech Christine turns to Dr. Jeff when her elderly Chihuahua has trouble walking; Dr. Jeff is called out to treat an alpaca with a serious infection.

Dr. Jeff gives hope to a concerned owner when their dog is diagnosed with cancer; the team cares for a litter of abandoned kittens; Dr. Amy solves the mystery of a beloved cat's painful injury; Dr. Jeff and Hector help a rescued tiger find love.

Dr. Jeff treats a skittish Savannah cat with an unusual condition; Dr. Amy helps a beloved dog who was injured chasing a coyote; the team tries to find the owners of a dog rescued on the highway.

Dr. Jeff helps a dog with a serious illness; Mel and her daughter rescue a baby squirrel; Dr. Jeff and Dr. Petra team up to save a beloved cat hit by a car; Dr. Baier gives a rabbit owner a surprise; a tiny dog with a big spirit needs a home.

A dog is lost during a windstorm; Dr. Baier treats a small bird that has a big personality; a paralyzed dog is abandoned; an alligator is injured in a fight.

Dr. Jeff treats a dog with a mysterious injury. Dr. Petra helps vet tech Jes' Dalmatian after it eats something toxic. A neglected turtle needs a new home, and the team falls in love with a litter of stray kittens.

A girl hopes Dr. Jeff can save her puppy from a deadly virus; a stray cat with a life-threatening injury; Dr. Jeff must gain the trust of rescued wolves to help an ailing member of the pack.