Life defined by height: in Turkey, the world's tallest woman lives with an unknown genetic condition linked to extreme growth and fragile bones, while in Brazil, the world's shortest couple navigate dwarfism and its physical challenges.

In Brazil, Claudio lives with a condition that bent his head backward; ahead of his 50th birthday, he wants to climb a sacred mountain; in Norway, Birgitte is training for the next Paralympics.

Winner of Uganda's Ugliest Man contest, Godfrey has a rare disorder that has left him disfigured. With 10 children, a new baby on the way, and his condition worsening, he is seeking medical answers that will determine his future.

Mark's hands are 20 times bigger than a normal adult male's.