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Murphy is confronted with corruption in the Colombian government once he tries to discolate Escobar's his political ambition together with his partner Peña.
The communistic radical group M-19 are counteracting the drug lords and Murphy's new partner Peña teaches him the Colombian way of law enforcement.
Despite a new extradition treaty, the USA is increasing their budget to fight communism. It will create new challenges for Murphy and Peña to hunt for Pablo Escobar.
As drug lord Pablo Escobar rises, Colombian and U.S. law enforcement find themselves battling an enemy who will do anything to keep his empire.