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After enjoying a relaxing cycle into work, Julian faces an uphill struggle at the Thirsk practice. A Large Munsterlander has a cancerous tumour on his jaw, and another vet has already recommended having him put to sleep. Can Julian offer any hope?
Peter's also on his bike, as he gears up for a 170-mile cross country challenge, as well as trying to help a red deer with a face abscess.
Matt meets a cow who's struggling to walk on a badly swollen knee, and David visits a rookie sheep farmer who has a poorly ram. But the bigger concern is that Blueberry might have made Muffin the ewe pregnant.
It is a landmark day at the hospital in Huddersfield as Shona Searson and the team use a new electro-chemotherapy treatment on a pet pygmy goat's cancerous tumour. Peter Wright heads into surgery with an elderly Lhasa apso that has been suffering with a painful eye problem, while Julian Norton deals with some rowdy alpacas.
A newborn lamb is brought to the hospital after being found abandoned by the roadside, and Matt and David have their work cut out to save its life. Elsewhere, Peter performs delicate surgery on a rat with a large tumour, and later, Julian's bank holiday barbecue is interrupted by a horse with suspected colic.
An old friend of Peter's heads to the practice with a sheep who birthed a lamb last night, but is struggling with her second. But neither vet nor farmer are optimistic about the unborn lamb's chances.
David rushes into the hospital with a terrier he knows well. His own rescue dog's best friend has ripped her ear on some barbed wire, so feels added pressure as he performs surgery.
Matt and a Herriot-loving American vet student operate on a cow with a twisted stomach. And, in Julian's words, it's "eyeball to eyeball, pig against vet" as he tries to remove a boar called Prince's tusks. But arguably he faces a bigger personal challenge with his latest dabble at DIY - trying to fix the door on the practice's new fridge.
A farmer's favourite calf struggles with a suspected hernia, but as Matt investigates, all might not be as expected. Julian heads into theatre to remove one of the largest lumps his team have ever seen on a dog, while Rohin faces challenging and delicate surgery to remove a pet mouse's eyeball.
Peter Wright treats two kittens that have been through unimaginable suffering after they were found dumped in a bag and set on fire. Elsewhere, Shona performs an emergency Caesarean to try and save a cow and her calf, and Julian hopes to help a dog suffering from a rare spinal condition.
Julian has a mysterious case on his hands when he treats two pet goats that have been attacked by an unknown animal. Elsewhere, Peter visit an old friend's farm where he meets a pig that is under the weather, and one of two dogs is guilty of eating some children's vitamin pills that could be fatal for whichever animal it was.
Peter treats a farmer's trusty Labrador that is struggling to walk after cutting herself badly on a nail. Elsewhere, Julian operates on a chicken with an infected leg, and Robin rushes to the aid of a pregnant ewe at one of the Huddersfield practice's smaller surgeries.
Peter has his hands full when not one, but two wild owls are brought into his practice in need of help, and Shona rushes to the aid of a horse that has tread on a nail, but she needs to assess the damage before she can remove it. Elsewhere, Julian has to learn sign language in order to communicate with a deaf dachshund in need of surgery.
Peter Wright treats a pet sheep with an unpleasant case of flystrike, resulting in an abundance of maggots living within its ear. Elsewhere, the Huddersfield team perform complicated spinal surgery on a French bulldog, and Julian Norton is called out to meet a pet pig called Pumba that has hay netting tangled around its teeth.
Matt Smith heads to Cannon Hall Farm where Rob and Dave's latest arrival, a Highland calf for whom they have high hopes as a future show champion, has serious breathing problems. Elsewhere, Rohin Aojula takes his dad on a call to help a horse that has suffered a nasty injury while out riding.
Julian operates on a French Bulldog that has injured one of his three legs, and vet Matt Smith rushes to a local farm to try and save a ewe and her unborn lamb. Elsewhere, Peter and Shona have some donkey work to do at the Greens' farm to solve a problem.
The Yorkshire Vet returns to follow all the drama, laughter and tears as a group of town and country vets, at four different practices across the county, help animals of all kinds. Christopher Timothy, who once played the world's most famous vet, James Herriot, provides the series narration.
Peter Wright, who was trained in Thirsk by Herriot himself, has more than 40 years' experience treating all kinds of animals. After leaving Skeldale Veterinary Centre, his old boss's original practice, he now works out of Grace Lane Vets in Kirkbymoorside, on the edge of the moors in North Yorkshire. Meanwhile, Julian Norton, Peter's former partner at Skeldale, has opened a practice back in Thirsk, which he runs alongside his wife, Anne. Julian is also a partner at Sandbeck Veterinary Centre in Wetherby, just across Yorkshire.
Following in their footsteps in upholding the Herriot ethos are a team of young vets at the Donaldson's practice in West Yorkshire. They include Matt Smith, Shona Searson, David Melleney and Rohin Aojula. Although they are based at a state-of-the-art animal hospital in Huddersfield, Donaldson's is another traditional mixed practice – their work involves caring for farm animals, wildlife and popular pets as well as some that are more exotic. The vets also encounter all kinds of colourful characters, from children to kindly old ladies to larger-than-life, straight-talking farmers.
Yorkshire is the series' other leading character. As we follow the vets to more remote farm locations, the countryside provides a stunning, ever-changing backdrop. And whatever the weather, they continue the Herriot tradition – treating all creatures great and small.