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The CSIs investigate a present-day crime with ties to a mob heist that occurred 25 years ago. Meanwhile, Brass has a decision to make when his daughter attempts suicide.
The CSIs investigate the cyber-related murder of a prominent casino owner's wife and receive help from the FBI's Cyber Crime Division.
The CSIs track a cannibalistic killer and discover he's not alone.
Russell is taken hostage after a teenager opens fire in a police station.
The CSIs are called to investigate when an entire family is reported to have been missing for a month.
The CSIs investigate the murder of a rock and roll groupie and the disappearance of a prostitute that both have ties to a mysterious band.
The CSIs investigate the murders of an Elvis impersonator and a bird that are strangely connected.
Nick and Greg investigate the death of a 16-year-old girl with ties to a brothel.
When the CSI team works two separate investigations, one involving a woman found murdered in Mexico and another of a local couple found dead in their driveway, they find the evidence in one case may help the other.
The CSIs are called to investigate a car crash and are shocked to discover the victim is someone they know.
Petty crime aboard an inbound plane to Vegas becomes a murder investigation when one of the passengers is found dead.
When a man is found murdered at an elaborate holiday party complete with real snow and live reindeer, the CSI team is brought in to investigate.
Spa weekend for Sara, Finlay and Morgan turns into a murder investigation and missing persons case when Finlay disappears, as the CSI team must piece together what happened in detail to find her.
The CSI team is called in to investigate the stabbing of a couple found at a local motel that is reminiscent of two incidents that occurred in the same room.
When a man is found dead inside a human-sized hamster ball, the CSI team is brought in to investigate. Also, the team collaborates with a swing shift CSI on a case involving a serial rapist.
The CSI team investigates a John Doe found during torrential rains in Vegas. Meanwhile, Greg Sanders is investigated and accused of framing a man for murder seven years ago.
The CSI team investigates the death of a homeless man who had a huge winning streak at a small casino.
Catherine Willows returns to help the CSIs solve a cold case that has haunted the team for 14 years.
When contestants on a reality cooking show accidentally eat human flesh during a competition, the CSI team is brought in to investigate.
The CSI team investigates a fire at a music venue that leaves four people dead, including two band members.
The CSI team is called in to investigate a murder and robbery at a poker game that had more than a million dollars in chips on the table.
Russell leads the CSI team on a hunt to find Morgan and Ellie Brass following their kidnapping by a ritualistic killer.
After 15 seasons and more than 300 episodes, the CSI team of D.B. Russell, Sara Sidle, Greg Sanders, Dr. Albert Robbins, David Phillips, David Hodges, Morgan Brody and Henry Andrews welcome back Gil Grissom, Catherine Willows and Jim Brass for their final case, when they investigate a catastrophic event that paralyzes all of Las Vegas. Russell and Sidle will make decisions regarding their crime-fighting careers, and the return of Lady Heather will create controversy one last time between Grissom and Sidle.