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House
After finally realizing that his Vicodin habit is distorting his view of reality, House voluntarily enters Mayfield Psychiatric Hospital to detox. However, detoxing turns out to be the easy part - House can't get his medical license back until he's willing to admit his problems run deeper. Although he resists at first, he finally gives in. At the same time, he falls in love, but then finds his paramour has no further interest in him. When he turns to his doctor instead of Vicodin for help, Dr. Nolan realizes he's ready to return to the practice of medicine.
Cuddy, House and members of the team join forces with a search-and-rescue team to provide much-needed medical attention at the scene of an emergency.
During a session with Dr. Nolan, House recounts the case of a woman who arrives at the Princeton Plainsboro emergency room with an unexplained illness and no recollection of who she is. While trying to solve the mystery of the woman's condition, House must also help her piece together her identity.
The team takes on the case of an ailing groom-to-be who harbors undisclosed secrets from a previous relationship. As his fiancée tries to get answers to her many questions, a frustrated team winnows down the possibilities. Meanwhile, House spends extra-curricular time with his Princeton Plainsboro colleagues at Wilson's insistence, performing a karaoke rendition of a Gladys Knight & The Pips classic with Foreman and Chase during a raucous night out.
House and the team take the case of a woman named Julia, who is in an open marriage and suddenly becomes ill during a date with her on-the-side boyfriend. Meanwhile, House tests Wilson's relationship with Sam.
House and the team take the case of Sir William, a knight from a community of men and women living according to the ideals of the High Renaissance. As the team searches the medieval village for environmental factors contributing to Sir William's rapidly deteriorating health, Thirteen and Sir William debate the acts that define honor and loyalty. Meanwhile, Wilson starts dating his ex-wife, Sam.
Princeton Plainsboro goes on lockdown when a newborn disappears from the nursery, preventing anyone from entering, leaving, or moving within the hospital. While House and his team members are trapped in various parts of the building, new insights surface about the team's personal lives, relationships, and regrets. Chase and Cameron finalize their divorce.
The team takes on the case of a high school senior who inexplicably blacks out during a class field trip and repeatedly hallucinates. Meanwhile, Taub airs his dirty laundry at work, and Wilson attempts to furnish his condo.
House and the team take on the case of an avid blogger admitted with sudden bruising and bleeding. From her hospital bed, the patient blogs about her symptoms, doctors, and prospective diagnoses to her dedicated band of followers and solicits their advice on a course of treatment. Wilson and House discover secrets about each other.
During a day in the life of Princeton Plainsboro's Dean of Medicine, Dr. Lisa Cuddy, the inner workings of the hospital are seen through her eyes. This day proves to be especially trying as Cuddy wrestles with myriad hospital issues and staff disputes that test her perseverance and skills as an administrator, all while juggling issues in her personal life.
House and the team rush to treat an ailing college football star in time for the patient to compete in NFL tryouts. But when the patient experiences an onslaught of varied and unusual symptoms, the team has trouble reaching a consensus on how to effectively treat him in time. Meanwhile, Foreman's brother Marcus makes a surprise visit to the hospital.
The team takes on the case of Valerie, an attractive female executive experiencing random episodes of excruciating pain. Meanwhile, House uncharacteristically attempts to alleviate his conscience by reaching out to a former medical school colleague he wronged.
When drug dealer Mickey mysteriously collapses while negotiating a sale, his partner-in-crime, Eddie, accompanies him to Princeton Plainsboro for treatment. But with a major deal pending, Mickey is not forthcoming with the necessary personal information the team needs to treat him. House and Wilson compete for a new neighbor's affection. Chase, Thirteen, and Taub play a practical joke.
When an old friend and former patient of Wilson's exhibits paralysis in his right arm, Wilson puts himself on the case. House wagers Wilson that the patient's symptoms are attributed to new cancer cells. Wilson accepts even though he is reluctant to believe cancer has returned. Cuddy continues her search for real estate.
On the eve of Thanksgiving, House and the team treat James Sidas, an exceptionally brilliant physicist and author who traded his successful career for a job as a courier. A myriad of strange symptoms nearly stumps the doctors. Also, they wrestle with strained personal relationships. Cameron left Chase to live in Chicago.
After House's medical license is reinstated, he reclaims his role as Head of Diagnostics in time to treat Hank Hardwick, an adult film star admitted to Princeton Plainsboro for pulsating eye pain. Meanwhile, Cuddy is reminded that the hospital is not conducive to healthy personal relationships, and House angles to form a dream team.
After a wild night out, a teenage girl is brought to Princeton Plainsboro with severely swollen appendages. Meanwhile, Cuddy and Wilson attend a medical conference for pharmacology and public policy. House tags along, planning to use the outing as an opportunity to push a personal agenda, but things don't go as expected.
The team takes on the case of a reckless police detective who has a family history of sudden heart failure that killed his father, grandfather and great-grandfather all at age 40. Meanwhile, Chase is haunted by his actions in the Dibala case, and House confronts some ghosts of his own.
A wealthy businessman brings his teenage son, who is suffering from inexplicable stomach pains, to Princeton Plainsboro and insists on having Dr. House handle the case. Meanwhile, Foreman and Chase prepare to present information on the Dibala case.
When a controversial African politician (guest star Jones) falls ill, he is brought to Princeton Plainsboro for treatment. The team struggles with whether to help a merciless dictator being subpoenaed for crimes against humanity in his country. Meanwhile, Wilson tries to make peace with a feuding neighbor, but House's prying exacerbates the problem.
House returns home to Princeton, where he continues to focus on his recovery but surprises Cuddy with the news that he's making a big change in his life. He's resigning. Meanwhile, the team cannot diagnose a loud-mouthed video game creator who posts each new symptom on the internet and opts for treatments suggested by the online community rather than by the doctors. Foreman angles for House's job, but the pressure to solve the case creates tension in his relationship with Thirteen. Taub quits when he learns that House isn't returning and begins searching for a new job.
House begins a detox program at Mayfield Psychiatric Hospital to get the Vicodin out of his system in an attempt to control his hallucinations.
House starts the year in prison, serving out a long term for his various misdeeds in Moving On. However, it turns out that he didn't even try to get a lesser sentence and took a one-year term without complaint. He blows a chance for early parole in order to prove a fellow patient's diagnosis. Although he plans to withdraw from the practice of medicine, it appears the real co-dependent relationship is between House and the hospital. With House looking at serving at least another six months, the new Dean of Medicine, Eric Foreman approaches House with an offer to return to work.
House and Cuddy make their relationship public, but despite the fact that they are both happier than they have been for years, they both see problems. House is sure that Cuddy is merely hopped up on the sex and good feelings that are typical early in the relationship and that she will dump him once she realizes what she's gotten herself into. Cuddy is sure that her supervisory role over House is either going to poison their relationship or ruin House's medical skills, and she's uncomfortable with many aspects of House's past, such as the prostitute he's still seeing for non-sexual purposes. House is also not certain he wants to have a role in Rachel Cuddy's life and starts to balk at the responsibility, although towards the end of the season, House and Rachel seem to share a strange bond over a cartoon about pirates.
After finally realizing that his Vicodin habit is distorting his view of reality, House voluntarily enters Mayfield Psychiatric Hospital to detox. However, detoxing turns out to be the easy part - House can't get his medical license back until he's willing to admit his problems run deeper. Although he resists at first, he finally gives in. At the same time, he falls in love, but then finds his paramour has no further interest in him. When he turns to his doctor instead of Vicodin for help, Dr. Nolan realizes he's ready to return to the practice of medicine.
Wilson slowly starts to recover from Amber's untimely death, but begins to reevaluate his life and to contemplate resigning from his post at the hospital. House's original regret over his role in Amber's death seems to have worn off as instead of being supportive, he merely tries to convince Wilson that he is overreacting to the situation. However, Wilson winds up leaving his post.
After losing his original diagnostic team, House decides that he doesn't need fellows as he feels that he can handle a case all on his own but after taking a long time to solve a case, Cuddy insists that he start looking for possible doctors to join his new team. House grudgingly accepts and gets forty applicants together and has a reality show style contest to see which lucky three applicants will stay on to get the vacant fellowship openings. Meanwhile, Cameron and Chase come back to work at the hospital, while Foreman starts work in a job similar to House's at another hospital. However, Foreman is soon fired for doing exactly what House would do and winds up back at Princeton-Plainsboro. House wants nothing to do with him, but Cuddy insists he can only hire two new fellows and must have Foreman on his team to keep an eye on him.
House recovers from his gunshot wounds, but despite his pain temporarily disappearing and the fact that his leg is working again, he is soon back on Vicodin. He runs into a particularly difficult patient at the clinic, who turns out to be a police officer, who then makes it his business to get House sent to jail for possessing Vicodin illegally. Unfortunately, House has used Wilson's prescription pad to forge his own prescriptions, even though Wilson has been supplying him with Vicodin freely. House nearly goes to jail, but Cuddy then perjures herself in court to have the charges dismissed.
Stacy Warner returns to PPTH, having been officially hired as the hospital's General Counsel. House eventually realizes that he still has feelings for her. In an attempt to prove that she feels the same way about him, he breaks into her therapist's office and reads her file. House learns that she is not sleeping with her husband Mark Warner. He tries to get back with her by killing a rat that has invaded her home, but soon changes his mind after learning that the rat has an illness that brings out the diagnostician in him.
We are introduced to the brilliant, famous but extremely exasperating Gregory House. We learn that despite his considerable intellect and talents as a physician, he does next to no work at the hospital, merely coming in from 9 to 5 to oversee his three teaching fellows. This infuriates his boss, Dean of Medicine Lisa Cuddy. However she keeps him on because when the rest of the doctors are stumped, House swings into action.
