Alexander meets King Charles with humility; Charles abandons Della Rovere; Lucrezia gives birth in a convent.

The invaders capture a pregnant Lucrezia who charms King Charles; Pope Alexander VI awaits his fate.

The invasion of France proceeds; Giovanni Sforza is poised to join the battle; Leonardo Da Vinci shares drawings and blueprints.

Della Rovere strikes a bargain with King Charles of France; Rodrigo attempts to thwart an invasion.

Lucrezia has an affair with a stable boy; Cesare strikes a bargain with Machiavelli and takes action to rid Ursula of her husband.

Lucrezia's wedding is a disaster; the Borgia children's mother arrives; Della Rovere seeks the aid of the Medici family.

Rodrigo seeks funds through a profitable marriage for Lucrezia and charges a fee for safe haven; the Borgias host a Turkish prince.

Micheletto, Orsini's assassin is recruited by Cesare to defect into the service of Della Rovere who is trying to prove Rodrigo has taken on a mistress.

Extremely ruthless and ambitious cardinal Rodrigo Borgia uses bribery to take advantage of the death of the current Pope and rise to the Papacy.