During her run, Eva finds an injured woman. When she tries to help her, she is kidnapped and locked up by a drug gang that has a score to settle with Bols. To free her, Wolfs and Bols are forced to work together. Marion and Romeo are given some time to prove that Marion's neighbor was offered on the internet for sexual purposes. Wolfs and Bols deal with the drug gang and Eva manages to escape, but Bols finds her first. During a shootout, Bols loses his life after Wolfs manages to take him out before Bols can take him out. As a result of the heroin previously administered to Eva, she has become addicted to it.

A young woman, mother of two children, is found dead in a tributary of the Meuse River. She left behind a suicide note, and the police conclude that she took her own life. But her mother, mayor of a village near Maastricht, cannot believe it and calls in Wolfs and Eva. Marion and Romeo investigate Marion's neighbor. Has she disappeared, and if so, what happened to her? Meanwhile, Bols tries to sell a large batch of cocaine and also has a hidden agenda.

A respectable student is found dead. The manner of his death points to a recently released criminal who collected debts for drug dealers. Was the boy involved in the drug world, or was his death related to his thesis? Marion and Romeo take care of a girl who was caught shoplifting.

During a shareholders' meeting of a wealthy family business, a murder is announced. The next morning, one of the sons is found dead in bed. It is up to Wolfs and Eva to find out whether it is murder and, if so, what the motive is. Romeo and Marion also have to deal with alleged wealth when a recognized refugee reports the theft of his lottery ticket, which has won a large sum of money. He is not the only one to report a crime.

A serial killer who attacks his victims from hiding places in the woods has claimed another victim. But unlike the first few times, there is a surviving witness. Wolfs and Eva are relentlessly hunting the killer, but he has a surprise in store for them. Romeo fines a woman with a sick child in her car. The woman reacts very violently to the fine. Marion wants to find out if there is more to the story.

Old ghosts resurface during the appeal of Jens Bols' family for the kidnapping of Eva. Wolfs tries to track down Bols, but he hasn't lost any of his old tricks. Romeo and Marion deal with a teacher who was assaulted while jogging in a park. However, she refuses to file a report. Marion gets to know her new neighbor better, and it's not exactly a pleasure.

An old case is reopened when Eva and Wolfs are confronted with the murder of a boy who was convicted 18 years earlier for the rape and manslaughter of a young girl. The detectives who investigated the rape using old methods impose themselves on Wolfs and Eva's investigation. Marion and Romeo also have to deal with old traumas when they investigate a theft in a nursing home.

A Bulgarian Roma girl is found murdered. It appears she gave birth shortly before her death. Eva and Wolfs, who is back at work, receive help from Interpol, a Bulgarian detective. But he turns out to have his own agenda. Romeo and Marion have to deal with a strangely helpful stalker.

Wolf infiltrates the organization of Amsterdam criminal Sjon. Eva, who doesn't get along with her new partner Peter Mooy, is with him on a case in Amsterdam. The victim in question turns out to be an old acquaintance of Eva's, Bea Middelkoop. She appears to have fallen from an apartment building. Marion and Romeo are dealing with a possible drug case.

Wolfs has left Maastricht, looks a lot different, and is out for revenge. Eva gets a new partner, Peter Mooy, who doesn't seem to be a good match. She is investigating a conflict between criminals from Maastricht and Amsterdam.