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Leonard and Penny's relationship takes a turn for the worse when they break up, but is quickly resolved. Soon their relationship progresses into a stronger friendship than before, while Sheldon and Penny's friendship slowly begins.
Penny is conflicted when Leonard and his friends decide to spend the summer working - at the North Pole.
Things begin to look up for Leonard when Penny makes a surprising revelation on her second date with Stuart. Meanwhile, Wolowitz enlists his friends' help when he discovers a critical design flaw in his project for NASA.
Leonard and Koothrappali take a heartbroken Wolowitz to Las Vegas, leaving Sheldon locked out of his apartment and forced to bunk with Penny.
While a fellow comic book-loving pal of the guys romances Penny, Leonard and Wolowitz venture out into the world of "Ladies' Night" at a local bar.
Penny develops a rivalry with a sexy female neighbor who threatens to become "The New Penny" in the building.
Penny's home hair products business becomes a complete nightmare when a caffeine-addled Sheldon takes over.
Train trip to San Francisco takes a major detour when Leonard, Sheldon, Wolowitz and Raj discover that beautiful sci-fi actress Summer Glau is onboard.
Paintball game leads to a fight between Penny and Sheldon, and romance for Wolowitz and Leslie.
Disastrous visit from Mrs. Hofstadter brings Leonard and Penny closer together.
Sheldon's "simple" solution to Penny's financial problem leads to a confrontation between Leonard and Penny's hulking ex-boyfriend, Kurt.
Socially awkward Sheldon develops a scientific procedure for making friends.
When Penny's comment about Wolowitz's love life sends him into a depressed stupor, his friends lose their most important team-mate in an upcoming fighting robot competition.
Christmas is a source of stress for Leonard - whose handsome colleague starts dating Penny - and his friends, who are being tormented by Sheldon's obsession with gift-giving etiquette.
When Leonard's relationship with a new woman starts moving too fast, he goes to Penny for advice.
Sheldon can barely contain his joy when Leonard starts dating a woman who meets Sheldon's exacting standards.
Wolowitz thinks he's found the love of his life, until she meets Leonard.
Penny vows to get revenge on Sheldon when he bans her from the apartment for a series of petty infractions.
Young grad student's attraction to Sheldon confuses everyone, including Sheldon himself.
Leonard and his friends stage an intervention to make Sheldon confront his longstanding fear of driving.
Raj, newly famous because of an article in a magazine, gets a big head and makes a disastrous play for Leonard's crush, Penny.
Sheldon creates a monster when he introduces Penny to the world of online gaming.
When Leonard sees Penny with a handsome new guy, he enters into a rebound relationship with Sheldon's nemesis, Leslie Winkle.
After her first date with Leonard goes awry, Penny finds an unwilling confidant in Leonard's anti-social roommate, Sheldon.
Sheldon and Amy's relationship takes a step forward, Penny makes big decisions in her professional and person life, Raj tries to prosper in the dating world with his newfound ability to talk to women, and Howard treats Bernadette to a very special surprise for the anniversary of their first date.
Howard return from space and adjust to normal, married life on earth. Sheldon and Amy's unique relationship continues to progress, though at a slower pace than Amy wants. Leonard and Penny's relationship is business as usual, with Leonard once again proposing to Penny. Meanwhile, Raj finally meets a girl and enters a (somewhat) stable relationship, the demise of which leads to unexpected progress for Raj.
Penny regrets her sleeping with Raj and has become very good friends with Leonard, Leonard breaks up with Priya, Amy pushes Sheldon in their relationship eventually becoming boyfriend and girlfriend, Penny and the other women become a clique of their own, Howard prepares for his wedding and going into space to the International Space Station and Leonard asks Penny out as they begin "Leonard and Penny 2.0".
Sheldon begins a platonic relationship with Amy, Howard reconnects with Bernadette eventually asking her to marry him, Leonard begins to date Raj's sister Priya, Penny becomes friends with Amy and expresses regret at breaking up with Leonard.
Penny throws herself at Leonard after he returns from three months at the North Pole and they begin a relationship, Penny and Sheldon start a quirky friendship though she can still annoy him, Howard begins to date Bernadette Rostenkowski and Sheldon meets Amy Farrah Fowler.
Leonard and Penny's relationship takes a turn for the worse when they break up, but is quickly resolved. Soon their relationship progresses into a stronger friendship than before, while Sheldon and Penny's friendship slowly begins.
The lives of physicists Dr. Leonard Hofstadter and Dr. Sheldon Cooper are shaken up when an attractive young aspiring actress from Omaha, Nebraska named Penny moves into the apartment across the hall from theirs. Leonard begins to become hopelessly enamored of Penny, while she feels only platonic affection for him; as a result, she finds herself putting up with his closest and ever-present friends: his roommate, Sheldon, who appears borderline obsessive-compulsive; engineering whiz Howard Wolowitz, a desperately sex-crazed mama's boy who thinks that his 1960s-style clothing and hairstyle give him an air of cool hipness; and Dr. Rajesh "Raj" Koothrappali, who will not speak to her as he is too shy to talk to women (a case of selective mutism), unless intoxicated in which case he becomes a smooth talking yet highly overly aggressive womanizing flirt.
