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Sheldon and Amy's relationship takes a step forward, Penny makes big decisions in her professional and person life, Raj tries to prosper in the dating world with his newfound ability to talk to women, and Howard treats Bernadette to a very special surprise for the anniversary of their first date.
Sheldon is forced to confront an uncertain future and considers a major move. Meanwhile, Raj and Emily take it to the next level, and Mrs. Wolowitz's injury is a major headache for Howard and Bernadette.
Bad day causes Penny to reevaluate her life choices - including Leonard. Meanwhile, Howard and Bernadette struggle to care for Mrs. Wolowitz, and Raj gets relationship advice from Sheldon.
Professor Proton helps Sheldon cope with grief, while Leonard turns a relationship milestone into a competition with Penny. Meanwhile, Amy and Bernadette make a "Star Wars Day" gift for the guys.
When Sheldon tries to be spontaneous, it leads to unexpected friction between Penny, Amy and Bernadette. Meanwhile, Raj seeks Howard's help in preparing for a date with Emily.
Sheldon faces a personal crisis after deciding he's wasting his time with string theory. Meanwhile, a double date between Raj, Emily and the Wolowitzes ends in embarrassment for Howard.
While Raj is wracked with guilt when he tries to date two women at once, Penny wrestles with whether to take a role in a cheesy movie and Sheldon is torn trying to choose between two gaming systems.
When Sheldon visits his Mom in Houston, he is forced to confront a new reality. Meanwhile, Raj's 'Murder Mystery' party starts some fights within the gang.
After the insults fly, Bernadette tries to broker the peace between Wolowitz and Sheldon. Meanwhile, Penny is offered an embarrassing movie role and Raj asks Amy to write to a woman on his behalf.
Leonard buys a dining room table and it causes Sheldon to reevaluate the changes in his life. Meanwhile, Wolowitz is offered a chance to go back to space and Bernadette struggles with whether or not to encourage him.
Love is in the air when Sheldon and Amy join Howard and Bernadette for a trip to wine country. Meanwhile, Leonard and Penny must rush Raj's dog to the vet.
After the guys can't get Comic-Con tickets, Sheldon tries to hold his own convention and winds up spending a wild night with James Earl Jones. Meanwhile, the girls see if they can act like "grown-ups".
Sheldon tries to relax after he is forced to take a vacation. Meanwhile, Leonard struggles to be supportive of Penny after she quits her job, and Bernadette seeks Stuart's help in replacing one of Howard's comic books.
When Penny's big acting break on NCIS is a bust, Leonard struggles to help her, which results in Penny asking Leonard a bold relationship question. Meanwhile, Sheldon tries to learn how to be funny and Raj tries to work on his "game" before talking to girls.
While Sheldon is away in Texas, everyone gathers to decorate the apartment Christmas tree, and they each realize how much he has changed their lives.
Leonard and Amy help Sheldon cope with the shame he's feeling after his accidental contribution to science is disproved. Meanwhile, Raj must stay with Howard and Bernadette for a week.
Sheldon protests when the gang drags him to Mrs. Wolowitz's house for Thanksgiving. Meanwhile, Penny and Leonard must deal with a mistake from her past.
Leonard tries to keep Sheldon from overreacting when a past mistake comes to light, but Sheldon punishes Leonard by making him walk a mile in his shoes. Meanwhile, Penny confronts Raj's ex-girlfriend, Lucy.
Sheldon feels slighted when Professor Proton seeks advice from Leonard instead of him, and he seeks revenge by befriending a rival science TV host, Bill Nye. Meanwhile, Raj gets jealous when Howard crashes "girls' night".
Sheldon's major scientific breakthrough makes him feel like a fraud. Meanwhile, Howard's romantic gesture to Bernadette causes Penny to step up her game with Leonard.
Sheldon must decide how much "Amy time" is too much after she takes a job at his university. Meanwhile, Howard finds himself sleeping on Raj's couch after a fight with Bernadette.
Sheldon seeks revenge after Amy ruins one of his favorite movies. Meanwhile, Leonard discovers a way to get Penny to do anything, and Raj and Stuart create online dating profiles.
When the entire gang competes in a scavenger hunt designed by Raj, it brings out the best - and worst - in everyone.
Leonard's friendship with Sheldon is put to the test when he returns from the North Sea. Meanwhile, Wolowitz's relationship with his mother causes an unusual threat to his masculinity.
With Leonard away, Sheldon and Penny spend quality time together sharing intimate secrets. Also, Wolowitz helps Raj get over his ex-girlfriend.
Sheldon and Amy's relationship takes a step forward, Penny makes big decisions in her professional and person life, Raj tries to prosper in the dating world with his newfound ability to talk to women, and Howard treats Bernadette to a very special surprise for the anniversary of their first date.
Howard return from space and adjust to normal, married life on earth. Sheldon and Amy's unique relationship continues to progress, though at a slower pace than Amy wants. Leonard and Penny's relationship is business as usual, with Leonard once again proposing to Penny. Meanwhile, Raj finally meets a girl and enters a (somewhat) stable relationship, the demise of which leads to unexpected progress for Raj.
Penny regrets her sleeping with Raj and has become very good friends with Leonard, Leonard breaks up with Priya, Amy pushes Sheldon in their relationship eventually becoming boyfriend and girlfriend, Penny and the other women become a clique of their own, Howard prepares for his wedding and going into space to the International Space Station and Leonard asks Penny out as they begin "Leonard and Penny 2.0".
Sheldon begins a platonic relationship with Amy, Howard reconnects with Bernadette eventually asking her to marry him, Leonard begins to date Raj's sister Priya, Penny becomes friends with Amy and expresses regret at breaking up with Leonard.
Penny throws herself at Leonard after he returns from three months at the North Pole and they begin a relationship, Penny and Sheldon start a quirky friendship though she can still annoy him, Howard begins to date Bernadette Rostenkowski and Sheldon meets Amy Farrah Fowler.
Leonard and Penny's relationship takes a turn for the worse when they break up, but is quickly resolved. Soon their relationship progresses into a stronger friendship than before, while Sheldon and Penny's friendship slowly begins.
The lives of physicists Dr. Leonard Hofstadter and Dr. Sheldon Cooper are shaken up when an attractive young aspiring actress from Omaha, Nebraska named Penny moves into the apartment across the hall from theirs. Leonard begins to become hopelessly enamored of Penny, while she feels only platonic affection for him; as a result, she finds herself putting up with his closest and ever-present friends: his roommate, Sheldon, who appears borderline obsessive-compulsive; engineering whiz Howard Wolowitz, a desperately sex-crazed mama's boy who thinks that his 1960s-style clothing and hairstyle give him an air of cool hipness; and Dr. Rajesh "Raj" Koothrappali, who will not speak to her as he is too shy to talk to women (a case of selective mutism), unless intoxicated in which case he becomes a smooth talking yet highly overly aggressive womanizing flirt.
