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Penny throws herself at Leonard after he returns from three months at the North Pole and they begin a relationship, Penny and Sheldon start a quirky friendship though she can still annoy him, Howard begins to date Bernadette Rostenkowski and Sheldon meets Amy Farrah Fowler.
While Penny worries that dating Leonard has ruined her for normal guys, Wolowitz and Koothrappali search for Sheldon's perfect match online.
Leonard tells Penny about how he met Sheldon for the first time...and what happened to the elevator.
Leonard and Sheldon compete for the attention of a famous female physicist.
When Leonard and Penny aren't speaking, Sheldon goes to extremes to keep them both happy.
Fight between Leonard and Penny threatens their relationship, while Sheldon battles Wil Wheaton in bowling.
Sheldon's friends come to his aid when his fear of public speaking stands between him and a coveted award.
When the guys find a ring from "The Lord of the Rings" at a garage sale, it threatens to tear them apart.
Sheldon winds up in traffic court when he gets a ticket because of Penny.
Leonard can only bring one guest on a trip to see CERN's Large Hadron Collider in Switzerland on Valentine's Day.
Sheldon's search for the answer to a physics problem leads him to work at the Cheesecake Factory with Penny.
When their apartment is robbed, Leonard and Sheldon turn to their friends to create a state-of-the-art security system.
While Sheldon and Koothrappali attend a university mixer, Leonard is upset to discover that Penny believes in psychics.
Visit from Leonard's mother delights Sheldon and horrifies Leonard.
Sheldon attempts to help Penny understand Leonard's work, and Wolowitz becomes jealous when Leonard starts hanging out with his new girlfriend.
After he's humiliated on National Public Radio, Sheldon vows to destroy Kripke, while Wolowitz tries not to destroy his new relationship with Bernadette.
With Leonard, Howard and Raj away camping in the desert, an injured Penny has only Sheldon to rely on.
An argument between Leonard and Penny proves "inconvenient" to Sheldon.
Sheldon teaches Leonard how to understand football while a kite-fighting incident threatens Howard and Raj's friendship.
While Sheldon settles a score with his nemesis, Wil Wheaton, Wolowitz begs Leonard to get Penny to set him up with one of her friends.
Raj must find a new job or be sent back to India, but Sheldon has a solution, which leaves Leonard and Penny dealing with Howard as third wheel.
Howard and Raj visit a Goth nightclub to pick up women while Sheldon attempts to build a better Penny using chocolate-based behavior modification.
Leonard and Penny struggle to recover from an awkward first hookup while Sheldon and Howard stake their best comic books on a bet to determine the species of a cricket.
Sheldon flees back to Texas in disgrace when he learns the guys tampered with his arctic expedition data, forcing the guys to follow him and threatening Leonard's hopes for a romantic encounter with Penny.
Sheldon and Amy's relationship takes a step forward, Penny makes big decisions in her professional and person life, Raj tries to prosper in the dating world with his newfound ability to talk to women, and Howard treats Bernadette to a very special surprise for the anniversary of their first date.
Howard return from space and adjust to normal, married life on earth. Sheldon and Amy's unique relationship continues to progress, though at a slower pace than Amy wants. Leonard and Penny's relationship is business as usual, with Leonard once again proposing to Penny. Meanwhile, Raj finally meets a girl and enters a (somewhat) stable relationship, the demise of which leads to unexpected progress for Raj.
Penny regrets her sleeping with Raj and has become very good friends with Leonard, Leonard breaks up with Priya, Amy pushes Sheldon in their relationship eventually becoming boyfriend and girlfriend, Penny and the other women become a clique of their own, Howard prepares for his wedding and going into space to the International Space Station and Leonard asks Penny out as they begin "Leonard and Penny 2.0".
Sheldon begins a platonic relationship with Amy, Howard reconnects with Bernadette eventually asking her to marry him, Leonard begins to date Raj's sister Priya, Penny becomes friends with Amy and expresses regret at breaking up with Leonard.
Penny throws herself at Leonard after he returns from three months at the North Pole and they begin a relationship, Penny and Sheldon start a quirky friendship though she can still annoy him, Howard begins to date Bernadette Rostenkowski and Sheldon meets Amy Farrah Fowler.
Leonard and Penny's relationship takes a turn for the worse when they break up, but is quickly resolved. Soon their relationship progresses into a stronger friendship than before, while Sheldon and Penny's friendship slowly begins.
The lives of physicists Dr. Leonard Hofstadter and Dr. Sheldon Cooper are shaken up when an attractive young aspiring actress from Omaha, Nebraska named Penny moves into the apartment across the hall from theirs. Leonard begins to become hopelessly enamored of Penny, while she feels only platonic affection for him; as a result, she finds herself putting up with his closest and ever-present friends: his roommate, Sheldon, who appears borderline obsessive-compulsive; engineering whiz Howard Wolowitz, a desperately sex-crazed mama's boy who thinks that his 1960s-style clothing and hairstyle give him an air of cool hipness; and Dr. Rajesh "Raj" Koothrappali, who will not speak to her as he is too shy to talk to women (a case of selective mutism), unless intoxicated in which case he becomes a smooth talking yet highly overly aggressive womanizing flirt.